Ischaemic and hypoxic conditioning: potential for protection of vital organs

JD Sprick, RT Mallet, K Przyklenk… - Experimental …, 2019 - Wiley Online Library
New Findings What is the topic of this review? Remote ischaemic preconditioning (RIPC)
and hypoxic preconditioning as novel therapeutic approaches for cardiac and …

Hemorheological and microcirculatory factors in liver ischemia-reperfusion injury—An update on pathophysiology, molecular mechanisms and protective strategies

N Nemeth, K Peto, Z Magyar, Z Klarik, G Varga… - International Journal of …, 2021 - mdpi.com
Hepatic ischemia-reperfusion injury (IRI) is a multifactorial phenomenon which has been
associated with adverse clinical outcomes. IRI related tissue damage is characterized by …

An ALOX12–12-HETE–GPR31 signaling axis is a key mediator of hepatic ischemia–reperfusion injury

XJ Zhang, XU Cheng, ZZ Yan, J Fang, X Wang… - Nature medicine, 2018 - nature.com
Hepatic ischemia–reperfusion (IR) injury is a common clinical issue lacking effective therapy
and validated pharmacological targets. Here, using integrative'omics' analysis, we identified …

Effect of remote ischemic preconditioning conducted in living liver donors on postoperative liver function in donors and recipients following liver transplantation: a …

KW Jung, J Kang, HM Kwon, YJ Moon, IG Jun, JG Song… - 2020 - journals.lww.com
Objective: This study aimed to assess the effects of remote ischemic preconditioning (RIPC)
on liver function in donors and recipients after living donor liver transplantation (LDLT) …

[PDF][PDF] Cytidine‐5'‐Diphosphocholine Protects the Liver From Ischemia/Reperfusion Injury Preserving Mitochondrial Function and Reducing Oxidative Stress

C Zazueta, M Buelna‐Chontal… - Liver …, 2018 - Wiley Online Library
Abstract Cytidine‐5'‐diphosphocholine (CDP‐choline) participates as an intermediary in the
synthesis of phosphatidylcholine, an essential component of cellular membranes. Citicoline …

TNFα‐Mediated Necroptosis Aggravates Ischemia‐Reperfusion Injury in the Fatty Liver by Regulating the Inflammatory Response

F Yang, L Shang, S Wang, Y Liu, H Ren… - Oxidative Medicine …, 2019 - Wiley Online Library
Nonalcoholic fatty liver disease (NAFLD) is more sensitive to ischemia and reperfusion
injury (IRI), while there are no effective methods to alleviate IRI. Necroptosis, also known as …

Ischemic preconditioning attenuates endoplasmic reticulum stress-dependent apoptosis of hepatocytes by regulating autophagy in hepatic ischemia-reperfusion injury

E Kong, Y Li, X Geng, J Wang, Y He, X Feng - International …, 2023 - Elsevier
Hepatic ischemia–reperfusion injury (HIRI) usually occurs during subtotal hepatectomy and
severely damages liver function during the perioperative period. Endoplasmic reticulum …

The hepatoprotective effect from ischemia‐reperfusion injury of remote ischemic preconditioning in the liver related surgery: a meta‐analysis

J Wu, C Yu, X Zeng, C Sun - ANZ Journal of Surgery, 2022 - Wiley Online Library
Background This study aimed to assess the hepatoprotective effect of remote ischemic
preconditioning (RIPC) in the liver related surgery. Methods Published articles in PubMed …

[HTML][HTML] SET8 mitigates hepatic ischemia/reperfusion injury in mice by suppressing MARK4/NLRP3 inflammasome pathway

Y Luo, Z Huang, T Mou, J Pu, T Li, Z Li, H Yang, P Yan… - Life Sciences, 2021 - Elsevier
Aims Hepatic ischemia/reperfusion (I/R) injury is a critical factor affecting the prognosis of
liver surgery. The aim of this study is to explore the effects of SET8 on hepatic I/R injury and …

The predictive value of graft viability and bioenergetics testing towards the outcome in liver transplantation

AT Meszaros, A Weissenbacher… - Transplant …, 2024 - frontierspartnerships.org
Donor organ biomarkers with sufficient predictive value in liver transplantation (LT) are
lacking. We herein evaluate liver viability and mitochondrial bioenergetics for their predictive …