The genetics of multiple sclerosis: an up‐to‐date review
Multiple sclerosis (MS) is a prevalent inflammatory disease of the central nervous system
that often leads to disability in young adults. Treatment options are limited and often only …
that often leads to disability in young adults. Treatment options are limited and often only …
Assessing the human immune system through blood transcriptomics
Blood is the pipeline of the immune system. Assessing changes in transcript abundance in
blood on a genome-wide scale affords a comprehensive view of the status of the immune …
blood on a genome-wide scale affords a comprehensive view of the status of the immune …
[BOOK][B] Textbook of personalized medicine
KK Jain - 2015 - Springer
Molecular diagnostics, the use of diagnostic testing to understand the molecular
mechanisms of an individual patient's disease, will be pivotal in the delivery of safe and …
mechanisms of an individual patient's disease, will be pivotal in the delivery of safe and …
Dissecting the heterogeneity of skin gene expression patterns in systemic sclerosis
Objective To examine the heterogeneity of global transcriptome patterns in systemic
sclerosis (SSc) skin in a large sample of patients with SSc and control subjects. Methods …
sclerosis (SSc) skin in a large sample of patients with SSc and control subjects. Methods …
Recommendations for clinical use of data on neutralising antibodies to interferon-beta therapy in multiple sclerosis
CH Polman, A Bertolotto, F Deisenhammer… - The Lancet …, 2010 - thelancet.com
The identification of factors that can affect the efficacy of immunomodulatory drugs in
relapsing-remitting multiple sclerosis (MS) is important. For the available interferon-beta …
relapsing-remitting multiple sclerosis (MS) is important. For the available interferon-beta …
[PDF][PDF] Impact of diagnosis and early treatment on the course of multiple sclerosis
Impact of Diagnosis and Early Treatment on the Course of Multiple Sclerosis Page 1 VOL. 19, NO.
17 ■ THE AMERICAN JOURNAL OF MANAGED CARE ■ S321 Multiple sclerosis (MS), a …
17 ■ THE AMERICAN JOURNAL OF MANAGED CARE ■ S321 Multiple sclerosis (MS), a …
[HTML][HTML] Vesicular stomatitis virus expressing interferon-β is oncolytic and promotes antitumor immune responses in a syngeneic murine model of non-small cell lung …
MR Patel, BA Jacobson, Y Ji, J Drees, S Tang… - Oncotarget, 2015 - ncbi.nlm.nih.gov
Vesicular stomatitis virus (VSV) is a potent oncolytic virus for many tumors. VSV that
produces interferon-β (VSV-IFNβ) is now in early clinical testing for solid tumors. Here, the …
produces interferon-β (VSV-IFNβ) is now in early clinical testing for solid tumors. Here, the …
Defining and scoring response to IFN-β in multiple sclerosis
The advent of a large number of new therapies for multiple sclerosis (MS) warrants the
development of tools that enable selection of the best treatment option for each new patient …
development of tools that enable selection of the best treatment option for each new patient …
Relationship between the type I interferon signature and the response to rituximab in rheumatoid arthritis patients
RM Thurlings, M Boumans, J Tekstra… - Arthritis & …, 2010 - Wiley Online Library
Objective To analyze the relationship between the type I interferon (IFN) signature and
clinical response to rituximab in rheumatoid arthritis (RA) patients. Methods Twenty RA …
clinical response to rituximab in rheumatoid arthritis (RA) patients. Methods Twenty RA …
Biomarkers of therapeutic response in multiple sclerosis: current status
VK Harris, SA Sadiq - Molecular diagnosis & therapy, 2014 - Springer
Multiple sclerosis (MS) is an autoimmune disease of unknown cause, in which chronic
inflammation drives multifocal demyelination of axons in both white and gray matter in the …
inflammation drives multifocal demyelination of axons in both white and gray matter in the …