Dietary fat and cancer—which is good, which is bad, and the body of evidence

B Bojková, PJ Winklewski… - International journal of …, 2020 - mdpi.com
A high-fat diet (HFD) induces changes in gut microbiota leading to activation of pro-
inflammatory pathways, and obesity, as a consequence of overnutrition, exacerbates …

How cancer cells remodel lipid metabolism: strategies targeting transcription factors

DW Jeong, S Lee, YS Chun - Lipids in Health and Disease, 2021 - Springer
Reprogramming of lipid metabolism has received increasing recognition as a hallmark of
cancer cells because lipid dysregulation and the alteration of related enzyme profiles are …

Omega-3 polyunsaturated fatty acids: moving towards precision use for prevention and treatment of colorectal cancer

J Aldoori, AJ Cockbain, GJ Toogood, MA Hull - Gut, 2022 - gut.bmj.com
Data from experimental studies have demonstrated that marine omega-3 polyunsaturated
fatty acids (O3FAs) have anti-inflammatory and anticancer properties. In the last decade …

Diet and gut microbes act coordinately to enhance programmed cell death and reduce colorectal cancer risk

RS Chapkin, SL Navarro, MAJ Hullar… - Digestive diseases and …, 2020 - Springer
Diet is an important risk factor for colorectal cancer (CRC), and several dietary constituents
implicated in CRC are modified by gut microbial metabolism. Microbial fermentation of …

Unveiling the MUFA–cancer connection: insights from endogenous and exogenous perspectives

Z Guo, KF Bergeron, M Lingrand… - International journal of …, 2023 - mdpi.com
Monounsaturated fatty acids (MUFAs) have been the subject of extensive research in the
field of cancer due to their potential role in its prevention and treatment. MUFAs can be …

Dietary fat and lipid metabolism in the tumor microenvironment

S Goswami, Q Zhang, CE Celik, EM Reich… - … et Biophysica Acta (BBA …, 2023 - Elsevier
Metabolic reprogramming has been considered a core hallmark of cancer, in which
excessive accumulation of lipids promote cancer initiation, progression and metastasis …

From food to genes: transcriptional regulation of metabolism by lipids and carbohydrates

I Bravo-Ruiz, MÁ Medina, B Martínez-Poveda - Nutrients, 2021 - mdpi.com
Lipids and carbohydrates regulate gene expression by means of molecules that sense these
macronutrients and act as transcription factors. The peroxisome proliferator-activated …

Flocculation of oleaginous green algae with Mortierella alpina fungi

T Shitanaka, L Higa, AE Bryson, C Bertucci… - Bioresource …, 2023 - Elsevier
Microalgae are promising sources of valuable bioproducts such as biofuels, food, and
nutraceuticals. However, harvesting microalgae is challenging due to their small size and …

Polyunsaturated fatty acids modulate the delivery of platelet microvesicle-derived microRNAs into human breast cancer cell lines

V Gasperi, C Vangapandu, I Savini… - The Journal of nutritional …, 2019 - Elsevier
Breast cancer is one of the most frequent and malignant types of cancer in women, with an
increasing morbidity and mortality rate; in particular, treatment of triple negative breast …

Low-level saturated fatty acid palmitate benefits liver cells by boosting mitochondrial metabolism via CDK1-SIRT3-CPT2 cascade

L Liu, B **e, M Fan, D Candas-Green, JX Jiang, R Wei… - Developmental cell, 2020 - cell.com
Saturated fatty acids (SFAs)(the" bad" fat), especially palmitate (PA), in the human diet are
blamed for potential health risks such as obesity and cancer because of SFA-induced …