Spontaneous subarachnoid haemorrhage

J Claassen, S Park - The Lancet, 2022 - thelancet.com
Subarachnoid haemorrhage (SAH) is the third most common subtype of stroke. Incidence
has decreased over past decades, possibly in part related to lifestyle changes such as …

Recovery from disorders of consciousness: mechanisms, prognosis and emerging therapies

BL Edlow, J Claassen, ND Schiff… - Nature Reviews Neurology, 2021 - nature.com
Substantial progress has been made over the past two decades in detecting, predicting and
promoting recovery of consciousness in patients with disorders of consciousness (DoC) …

Detection of brain activation in unresponsive patients with acute brain injury

J Claassen, K Doyle, A Matory, C Couch… - … England Journal of …, 2019 - Mass Medical Soc
Background Brain activation in response to spoken motor commands can be detected by
electroencephalography (EEG) in clinically unresponsive patients. The prevalence and …

Robust EEG-based cross-site and cross-protocol classification of states of consciousness

DA Engemann, F Raimondo, JR King, B Rohaut… - Brain, 2018 - academic.oup.com
Determining the state of consciousness in patients with disorders of consciousness is a
challenging practical and theoretical problem. Recent findings suggest that multiple markers …

[HTML][HTML] Accuracy of EEG biomarkers in the detection of clinical outcome in disorders of consciousness after severe acquired brain injury: preliminary results of a pilot …

F Di Gregorio, F La Porta, V Petrone, S Battaglia… - Biomedicines, 2022 - mdpi.com
Accurate outcome detection in neuro-rehabilitative settings is crucial for appropriate long-
term rehabilitative decisions in patients with disorders of consciousness (DoC). EEG …

Clinical and advanced neurophysiology in the prognostic and diagnostic evaluation of disorders of consciousness: review of an IFCN-endorsed expert group

A Comanducci, M Boly, J Claassen, M De Lucia… - Clinical …, 2020 - Elsevier
The analysis of spontaneous EEG activity and evoked potentials is a cornerstone of the
instrumental evaluation of patients with disorders of consciousness (DoC). The past few …

Consciousness and complexity: a consilience of evidence

S Sarasso, AG Casali, S Casarotto… - Neuroscience of …, 2021 - academic.oup.com
Over the last years, a surge of empirical studies converged on complexity-related measures
as reliable markers of consciousness across many different conditions, such as sleep …

Cognitive motor dissociation: gap analysis and future directions

J Claassen, D Kondziella, A Alkhachroum, M Diringer… - Neurocritical care, 2024 - Springer
Background Patients with disorders of consciousness who are behaviorally unresponsive
may demonstrate volitional brain responses to motor imagery or motor commands …

The curing coma campaign: framing initial scientific challenges—proceedings of the first curing coma campaign scientific advisory council meeting

JJ Provencio, JC Hemphill, J Claassen, BL Edlow… - Neurocritical care, 2020 - Springer
Coma and disordered consciousness are common manifestations of acute neurological
conditions and are among the most pervasive and challenging aspects of treatment in …

Ketamine to treat super-refractory status epilepticus

A Alkhachroum, CA Der-Nigoghossian, E Mathews… - Neurology, 2020 - neurology.org
Objective To test ketamine infusion efficacy in the treatment of super-refractory status
epilepticus (SRSE), we studied patients with SRSE who were treated with ketamine …