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Therapeutic roles of mesenchymal stem cell-derived extracellular vesicles in cancer
Z Weng, B Zhang, C Wu, F Yu, B Han, B Li… - Journal of hematology & …, 2021 - Springer
Extracellular vesicles (EVs) are cell-derived membrane structures enclosing proteins, lipids,
RNAs, metabolites, growth factors, and cytokines. EVs have emerged as essential …
RNAs, metabolites, growth factors, and cytokines. EVs have emerged as essential …
Engineered extracellular vesicles for cancer therapy
X Zhang, H Zhang, J Gu, J Zhang, H Shi… - Advanced …, 2021 - Wiley Online Library
Extracellular vesicles (EVs) have emerged as a novel cell‐free strategy for the treatment of
many diseases including cancer. As a result of their natural properties to mediate cell‐to‐cell …
many diseases including cancer. As a result of their natural properties to mediate cell‐to‐cell …
Polydopamine decorated microneedles with Fe‐MSC‐derived nanovesicles encapsulation for wound healing
W Ma, X Zhang, Y Liu, L Fan, J Gan, W Liu… - Advanced …, 2022 - Wiley Online Library
Wound dressing with the capacities of antioxidation, antiinflammation, and efficient
angiogenesis induction is expected for effectively promoting wound healing. Herein, a novel …
angiogenesis induction is expected for effectively promoting wound healing. Herein, a novel …
Exosome-mediated delivery of kartogenin for chondrogenesis of synovial fluid-derived mesenchymal stem cells and cartilage regeneration
X Xu, Y Liang, X Li, K Ouyang, M Wang, T Cao, W Li… - Biomaterials, 2021 - Elsevier
Transplantation of synovial fluid-derived mesenchymal stem cells (SF-MSCs) is a viable
therapy for cartilage degeneration of osteoarthritis (OA). But controlling chondrogenic …
therapy for cartilage degeneration of osteoarthritis (OA). But controlling chondrogenic …
Treatment with mesenchymal stem cell‐derived nanovesicle‐containing gelatin methacryloyl hydrogels alleviates osteoarthritis by modulating chondrogenesis and …
L Pang, H **, Z Lu, F **e, H Shen, X Li… - Advanced …, 2023 - Wiley Online Library
Osteoarthritis is a degenerative disorder that can severely affect joints, and new treatment
strategies are urgently needed. Administration of mesenchymal stem cell (MSC)‐derived …
strategies are urgently needed. Administration of mesenchymal stem cell (MSC)‐derived …
Exosomes and exosome-inspired vesicles for targeted drug delivery
The similarities between exosomes and liposomes, together with the high organotropism of
several types of exosomes, have recently prompted the development of engineered …
several types of exosomes, have recently prompted the development of engineered …
Collagen type I biomaterials as scaffolds for bone tissue engineering
GA Rico-Llanos, S Borrego-González… - Polymers, 2021 - mdpi.com
Collagen type I is the main organic constituent of the bone extracellular matrix and has been
used for decades as scaffolding material in bone tissue engineering approaches when …
used for decades as scaffolding material in bone tissue engineering approaches when …
M1 macrophage-derived nanovesicles potentiate the anticancer efficacy of immune checkpoint inhibitors
Cancer immunotherapy modulates immune cells to induce antitumor immune responses.
Tumors employ immune checkpoints to evade immune cell attacks. Immune checkpoint …
Tumors employ immune checkpoints to evade immune cell attacks. Immune checkpoint …
Development of extracellular vesicle therapeutics: Challenges, considerations, and opportunities
Extracellular vesicles (EVs) hold great promise as therapeutic modalities due to their
endogenous characteristics, however, further bioengineering refinement is required to …
endogenous characteristics, however, further bioengineering refinement is required to …
Mesenchymal stem cell-derived magnetic extracellular nanovesicles for targeting and treatment of ischemic stroke
HY Kim, TJ Kim, L Kang, YJ Kim, MK Kang, J Kim… - Biomaterials, 2020 - Elsevier
Exosomes and extracellular nanovesicles (NV) derived from mesenchymal stem cells (MSC)
may be used for the treatment of ischemic stroke owing to their multifaceted therapeutic …
may be used for the treatment of ischemic stroke owing to their multifaceted therapeutic …