The last few years has seen rapid advances in the solid phase synthesis of oligonucleotides
(reviewed by Itakura et al., 1984; Gait, 1984; Caruthers, 1985) which combined with the …

SCIENCE Page 1 20 September 1985, Volume 229, Number 4719 SCIENCE David Botstein
and David Shortie Summary. The many mutagenesis strategies made possible by the …

Recent studies suggest that the fly uses the inositol lipid signaling system for visual
excitation and that the Drosophila transient receptor potential (trp) mutation disrupts this …

In response to the emergence of pathogenic bacteria that cannot be treated with current
antibiotics, many researchers are revisiting the use of bacteriophages, or phages, to fight …

The construction and purification of recombinant baculovirus vectors for the expression of
foreign genes in insect cells by standard transfection and plaque assay methods can take as …

The genomic RNA of the coronavirus IBV contains an efficient ribosomal frameshifting signal
at the junction of two overlap** open reading frames. We have defined by deletion …

The transposable IFP2 element of Trichoplusia ni was originally isolated as a host DNA
insertion in spontaneous FP mutants of Galleria mellonella or Autographa californica …

The primary structure of the major embryonic Notch transcript is presented, as determined by
sequence analysis of overlap** cDNA clones. The 10,148 bp sequence corresponding to …

We have isolated and analyzed DNA sequences encompassing the period (Per) locus of
Drosophila melanogaster. The location of this clock gene was delimited by the molecular …

We have developed a gene-fusion system based on the Escherichia coli beta-glucuronidase
gene (uidA). The uidA gene has been cloned from E. coli K-12 and its entire nucleotide …