Ischemic stroke is a leading cause of death worldwide; currently available treatment
approaches for ischemic stroke are to restore blood flow, which reduce disability but are time …

A direct and an indirect relationship between paraoxonase 1 (PON1) and atherosclerosis
exists. Given PON1's physical location within high‐density lipoprotein (HDL) particles and its …

Cerebrovascular diseases and the subsequent brain hypoperfusion are at the basis of
vascular dementia. Dyslipidemia, marked by an increase in circulating levels of triglycerides …

Abstract Peroxynitrite (ONOO−)-mediated mitophagy activation represents a vital pathogenic
mechanism in ischemic stroke. Our previous study suggests that ONOO− mediates Drp1 …

Ischemic stroke is a serious public health problem worldwide. Here, we characterized the
metabolite features of acute ischemic stroke (AIS) using a gas chromatography-mass …

Polycystic ovary syndrome (PCOS) is associated with altered lipid profile and increased
small, dense LDL particles (sdLDL). Considering that paraoxonase 1 (PON1) is an …

Osteoarthritis represents a leading cause of disability with limited treatment options.
Furthermore, it is frequently accompanied by cardiovascular and cognitive disorders, which …

Aging and major chronic diseases are risk factors for lower urinary tract symptoms (LUTS).
On the other hand, oxidative stress (OS) is one of the fundamental mechanisms of aging and …

Cerebral ischemia-reperfusion injury (CIRI) refers to a secondary brain injury that occurs
when blood supply is restored to ischemic brain tissue and is one of the leading causes of …

This study aimed to identify the effect of β-caryophyllene (BCP) pretreatment and elucidate
the Nrf2/HO-1 signaling mechanism after focal cerebral ischemia-reperfusion (IR) injury in …