Recent advances in biologically active coumarins from marine sources: Synthesis and evaluation

L Fernández-Peña, MJ Matos, E López - Marine Drugs, 2022 - mdpi.com
Coumarin and its derivatives have significantly attracted the attention of medicinal chemists
and chemical biologists due to their huge range of biological, and in particular …

6, 7-Coumarin-heterocyclic hybrids: a comprehensive review of their natural sources, synthetic approaches, and bioactivity

NM Zeki, YF Mustafa - Journal of Molecular Structure, 2024 - Elsevier
The hybridization of heterocycles presents a key opportunity to craft innovative multicyclic
compounds with enhanced biological activity. Coumarins, being broadly prevalent natural …

[PDF][PDF] Novel coumarins isolated from the seeds of Citrullus lanatus as potential antimicrobial agents

RM Jebir, YF Mustafa - Eurasian Chemical Communications, 2022 - sid.ir
The universal rise in the outbreak and fatality rates related to multidrug-resistant
microorganisms is a growing problem worldwide that necessitates the emergence of new …

Coumarin hybrids for targeted therapies: A promising approach for potential drug candidates

NM Zeki, YF Mustafa - Phytochemistry Letters, 2024 - Elsevier
Phyto-coumarins demonstrate diverse biological actions, encompassing antiradical, anti-
inflammatory, oncolytic, monoamine oxidase B (MAOB) suppression, and antibacterial …

Synthesis of 7, 8-dihydroxy-4-phenylbenzo [g] coumarins as potential multitarget anti-skin-aging candidates

YF Mustafa - Journal of Molecular Structure, 2025 - Elsevier
Skin aging is a gradual, spontaneous, slow-processing, and natural phenomenon that
induces a negative impact on the skin's function and structure. Numerous cosmoceutical …

3-mercaptocoumarins as potential bioactive candidates: From novel synthesis to comparative analysis

YF Mustafa - Journal of Molecular Structure, 2025 - Elsevier
In the literature, only two papers describe the synthesis of 3-mercaptocoumarins (3-MCMs)
without exploring their bioactivity. So, the novelty of this work is driven by the fact that it …

Synthesis of novel 6-aminocoumarin derivatives as potential–biocompatible antimicrobial and anticancer agents

YF Mustafa - Journal of Molecular Structure, 2025 - Elsevier
Among the most health-influencing threats, microbial infections and cancer have attracted a
mounting interest in the medical field. To face these threats, research is directed to improve …

[HTML][HTML] Linearly ring-fused coumarins: A review of their cancer-fighting attributes

RN Jibroo, YF Mustafa - Results in Chemistry, 2024 - Elsevier
Despite the up-to-date advancements in its treatment, cancer is still being harvested the
lives of millions of people annually; this health threat necessitates exploring more potent …

Annulated Heterocyclic[g]Coumarin Composites: Synthetic Approaches and Bioactive Profiling

N Mazin Zeki, Y Fakri Mustafa - Chemistry & Biodiversity, 2024 - Wiley Online Library
Coumarins, widely abundant natural heterocyclic compounds, are extensively employed in
creating various biologically and pharmacologically potent substances. The hybridization of …

A narrative review of benzo-fused coumarins, shedding light on their medicinal activities

Y Mustafa, S Waheed, S Jasim, R Jebir… - Iraqi Journal of …, 2023 - iphr.mosuljournals.com
Background: Coumarins and their derivatives excel in chemical diversity, coupled with a
wide variety of biological potentials, and tend to be beneficial to the health of the human …