Unravelling cell migration: defining movement from the cell surface
F Merino-Casallo, MJ Gomez-Benito… - Cell adhesion & …, 2022 - Taylor & Francis
Cell motility is essential for life and development. Unfortunately, cell migration is also linked
to several pathological processes, such as cancer metastasis. Cells' ability to migrate relies …
to several pathological processes, such as cancer metastasis. Cells' ability to migrate relies …
Fibroblast growth factor receptors (FGFRs) and noncanonical partners in cancer signaling
HR Ferguson, MP Smith, C Francavilla - Cells, 2021 - mdpi.com
Increasing evidence indicates that success of targeted therapies in the treatment of cancer is
context-dependent and is influenced by a complex crosstalk between signaling pathways …
context-dependent and is influenced by a complex crosstalk between signaling pathways …
Stiffness-dependent active wetting enables optimal collective cell durotaxis
ME Pallarès, I Pi-Jaumà, IC Fortunato, V Grazu… - Nature Physics, 2023 - nature.com
The directed migration of cellular clusters enables morphogenesis, wound healing and
collective cancer invasion. Gradients of substrate stiffness direct the migration of cellular …
collective cancer invasion. Gradients of substrate stiffness direct the migration of cellular …
New developments in the biology of fibroblast growth factors
DM Ornitz, N Itoh - WIREs mechanisms of disease, 2022 - Wiley Online Library
The fibroblast growth factor (FGF) family is composed of 18 secreted signaling proteins
consisting of canonical FGFs and endocrine FGFs that activate four receptor tyrosine …
consisting of canonical FGFs and endocrine FGFs that activate four receptor tyrosine …
Cadherin expression and EMT: A focus on gliomas
Cadherins are calcium-binding proteins with a pivotal role in cell adhesion and tissue
homeostasis. The cadherin-dependent mechanisms of cell adhesion and migration are …
homeostasis. The cadherin-dependent mechanisms of cell adhesion and migration are …
Patient selection approaches in FGFR inhibitor trials—many paths to the same end?
P Ellinghaus, D Neureiter, H Nogai, S Stintzing… - Cells, 2022 - mdpi.com
Inhibitors of fibroblast growth factor receptor (FGFR) signaling have been investigated in
various human cancer diseases. Recently, the first compounds received FDA approval in …
various human cancer diseases. Recently, the first compounds received FDA approval in …
Long noncoding RNA LINC00982 upregulates CTSF expression to inhibit gastric cancer progression via the transcription factor HEY1
L Zheng, J Cao, L Liu, H Xu, L Chen… - American Journal of …, 2021 - journals.physiology.org
Upregulating the expression of long noncoding RNA LINC00982 controlled cell proliferation
in gastric cancer, but the regulatory molecular mechanisms are yet to be expounded. We …
in gastric cancer, but the regulatory molecular mechanisms are yet to be expounded. We …
Diverse Fgfr1 signaling pathways and endocytic trafficking regulate mesoderm development
The fibroblast growth factor (FGF) pathway is a conserved signaling pathway required for
embryonic development. Activated FGF receptor 1 (FGFR1) drives multiple intracellular …
embryonic development. Activated FGF receptor 1 (FGFR1) drives multiple intracellular …
Prevented Cell Clusters' Migration Via Microdot Biomaterials for Inhibiting Scar Adhesion
Y Zhuang, F Lin, L **ang, Z Cai, F Wang… - Advanced …, 2024 - Wiley Online Library
Cluster‐like collective cell migration of fibroblasts is one of the main factors of adhesion in
injured tissues. In this research, a microdot biomaterial system is constructed using α‐helical …
injured tissues. In this research, a microdot biomaterial system is constructed using α‐helical …
Human amniotic membrane scaffold enhances adipose mesenchymal stromal cell mitochondrial bioenergetics promoting their regenerative capacities
AM Abou-Shanab, OA Gaser, MW Soliman… - Molecular and Cellular …, 2024 - Springer
The human amniotic membrane (hAM) has been applied as a scaffold in tissue engineering
to sustain stem cells and enhance their regenerative capacities. We investigated the …
to sustain stem cells and enhance their regenerative capacities. We investigated the …