UroPathogenic Escherichia coli (UPEC) Infections: Virulence Factors, Bladder Responses, Antibiotic, and Non-antibiotic Antimicrobial Strategies

ME Terlizzi, G Gribaudo, ME Maffei - Frontiers in microbiology, 2017 - frontiersin.org
Urinary tract infections (UTIs) are one of the most common pathological conditions in both
community and hospital settings. It has been estimated that about 150 million people …

Urinary tract infection: pathogenesis and outlook

LK McLellan, DA Hunstad - Trends in molecular medicine, 2016 - cell.com
The clinical syndromes comprising urinary tract infection (UTI) continue to exert significant
impact on millions of patients worldwide, most of whom are otherwise healthy women …

[HTML][HTML] Bacterial autoaggregation

T Trunk, HS Khalil, JC Leo - AIMS microbiology, 2018 - ncbi.nlm.nih.gov
Many bacteria, both environmental and pathogenic, exhibit the property of autoaggregation.
In autoaggregation (sometimes also called autoagglutination or flocculation), bacteria of the …

Urinary tract infection: Pathogenicity, antibiotic resistance and development of effective vaccines against Uropathogenic Escherichia coli

MRA Karam, M Habibi, S Bouzari - Molecular immunology, 2019 - Elsevier
Urinary tract infections (UTIs) are recognized as one of the most common infectious
diseases in the world that can be divided to different types. Uropathogenic Escherichia coli …

Pathogenicity Factors of Genomic Islands in Intestinal and Extraintestinal Escherichia coli

M Desvaux, G Dalmasso, R Beyrouthy… - Frontiers in …, 2020 - frontiersin.org
Escherichia coli is a versatile bacterial species that includes both harmless commensal
strains and pathogenic strains found in the gastrointestinal tract in humans and warm …

Urinary Tract Infections Caused by Uropathogenic Escherichia coli: Mechanisms of Infection and Treatment Options

Y Zhou, Z Zhou, L Zheng, Z Gong, Y Li, Y **… - International journal of …, 2023 - mdpi.com
Urinary tract infections (UTIs) are common bacterial infections that represent a severe public
health problem. They are often caused by Escherichia coli (E. coli), Klebsiella pneumoniae …

Type V secretion systems: an overview of passenger domain functions

I Meuskens, A Saragliadis, JC Leo… - Frontiers in microbiology, 2019 - frontiersin.org
Bacteria secrete proteins for different purposes such as communication, virulence functions,
adhesion to surfaces, nutrient acquisition, or growth inhibition of competing bacteria. For …

Drug and vaccine development for the treatment and prevention of urinary tract infections

VP O'brien, TJ Hannan, HV Nielsen… - Urinary Tract Infections …, 2017 - Wiley Online Library
Urinary tract infections (UTI) are one of the most common bacterial infections, with roughly
eleven‐million cases reported in the US each year that cost an estimated $5 billion annually …

How can vaccines contribute to solving the antimicrobial resistance problem?

M Lipsitch, GR Siber - MBio, 2016 - Am Soc Microbiol
There is a growing appreciation for the role of vaccines in confronting the problem of
antimicrobial resistance (AMR). Vaccines can reduce the prevalence of resistance by …

Intestinal Pathogenic Escherichia coli: Insights for Vaccine Development

M Rojas-Lopez, R Monterio, M Pizza… - Frontiers in …, 2018 - frontiersin.org
Diarrheal diseases are one of the major causes of mortality among children under five years
old and intestinal pathogenic Escherichia coli (InPEC) plays a role as one of the large …