The endothelium is a dynamic, semipermeable layer lining all blood vessels, regulating
blood vessel formation and barrier function. Proper composition and function of the …

Integrins are transmembrane heterodimeric proteins sensing the cell microenvironment and
modulating numerous signalling pathways. Changes in integrin expression between normal …

E-cadherin loss is frequently associated with ovarian cancer metastasis. Given that
adhesion to the abdominal peritoneum is the first step in ovarian cancer dissemination, we …

Tenascin-C is an adhesion modulatory extracellular matrix molecule that is highly expressed
in the microenvironment of most solid tumors. High tenascin-C expression reduces the …

The role of the fibronectin receptor, α 5 β 1-integrin, as an adhesion receptor and in
angiogenesis is well established. However, its role in cancer cell invasion and metastasis is …

Angiogenesis, the formation of new blood vessels from preexisting vasculature, contributes
to the pathogenesis of many disorders, including ischemic diseases and cancer. Integrins …

Tumor growth and progression rely upon angiogenesis, which is regulated by pro-and
antiangiogenic factors, including members of the semaphorin family. By analyzing 3 different …

Abstract Galectin-1 (Gal-1), a homodimeric prototype of the galectins with a single
carbohydrate-recognition domain, was recently identified as being overexpressed in tumor …

Imaging of lymphangiogenesis and angiogenesis requires robust and unambiguous
markers of lymphatic and blood vessels. Although much progress has been made in recent …

Engineering biomaterials with integrin‐binding activity is a very powerful approach to
promote cell adhesion, modulate cell behavior, and induce specific biological responses at …