Nanomaterial-based contrast agents

JC Hsu, Z Tang, OE Eremina, AM Sofias… - Nature Reviews …, 2023 - nature.com
Medical imaging, which empowers the detection of physiological and pathological
processes within living subjects, has a vital role in both preclinical and clinical diagnostics …

[HTML][HTML] Biodistribution, pharmacokinetics and excretion studies of intravenously injected nanoparticles and extracellular vesicles: Possibilities and challenges

T Skotland, TG Iversen, A Llorente, K Sandvig - Advanced drug delivery …, 2022 - Elsevier
There is a large interest in develo** nanoparticles and extracellular vesicles for delivery of
therapeutics or imaging agents. Regulatory approval of such products requires knowledge …

Nanoparticle contrast agents for X‐ray imaging applications

JC Hsu, LM Nieves, O Betzer, T Sadan… - Wiley …, 2020 - Wiley Online Library
X‐ray imaging is the most widely used diagnostic imaging method in modern medicine and
several advanced forms of this technology have recently emerged. Iodinated molecules and …

Biomedical imaging: principles, technologies, clinical aspects, contrast agents, limitations and future trends in nanomedicines

J Wallyn, N Anton, S Akram, TF Vandamme - Pharmaceutical research, 2019 - Springer
This review article presents the state-of-the-art in the major imaging modalities supplying
relevant information on patient health by real-time monitoring to establish an accurate …

[PDF][PDF] Smart albumin‐biomineralized nanocomposites for multimodal imaging and photothermal tumor ablation

Y Wang, T Yang, H Ke, A Zhu, Y Wang, J Wang… - Advanced …, 2015 - researchgate.net
For example, several theranostic nanoparticles integrating MR imaging with fluorescence or
CT exhibit considerable advantages of imaging features for tumor detection, treatment …

Molecular imaging nanoprobes for theranostic applications

H He, X Zhang, L Du, M Ye, Y Lu, J Xue, J Wu… - Advanced Drug Delivery …, 2022 - Elsevier
As a non-invasive imaging monitoring method, molecular imaging can provide the location
and expression level of disease signature biomolecules in vivo, leading to early diagnosis of …

Opportunities for new CT contrast agents to maximize the diagnostic potential of emerging spectral CT technologies

BM Yeh, PF FitzGerald, PM Edic, JW Lambert… - Advanced drug delivery …, 2017 - Elsevier
The introduction of spectral CT imaging in the form of fast clinical dual-energy CT enabled
contrast material to be differentiated from other radiodense materials, improved lesion …

Metal–organic framework (MOF)-based nanomaterials for biomedical applications

Z Luo, S Fan, C Gu, W Liu, J Chen… - Current medicinal …, 2019 - benthamdirect.com
Background: Metal-organic frameworks (MOFs), as a new class of porous organic-inorganic
crystalline hybrid materials that governed by the self-assembled of metal atoms and organic …

In vivo small animal micro-CT using nanoparticle contrast agents

JR Ashton, JL West, CT Badea - Frontiers in pharmacology, 2015 - frontiersin.org
Computed tomography (CT) is one of the most valuable modalities for in vivo imaging
because it is fast, high-resolution, cost-effective, and non-invasive. Moreover, CT is heavily …

Advantages and limitations of current techniques for analyzing the biodistribution of nanoparticles

L Arms, DW Smith, J Flynn, W Palmer… - Frontiers in …, 2018 - frontiersin.org
Nanomedicines are typically submicrometer-sized carrier materials (nanoparticles)
encapsulating therapeutic and/or imaging compounds that are used for the prevention …