Abstract Machine learning is increasingly important in microbiology where it is used for tasks
such as predicting antibiotic resistance and associating human microbiome features with …

Posttranslational modifications (PTMs) refer to amino acid side chain modification in some
proteins after their biosynthesis. There are more than 400 different types of PTMs affecting …

The ConSurf web‐sever for the analysis of proteins, RNA, and DNA provides a quick and
accurate estimate of the per‐site evolutionary rate among homologues. The analysis reveals …

RNA 3D structure prediction is a long-standing challenge. Inspired by the recent
breakthrough in protein structure prediction, we developed trRosettaRNA, an automated …

Transmembrane proteins span the lipid bilayer and are divided into two major structural
classes, namely alpha helical and beta barrels. We introduce DeepTMHMM, a deep …

Anthropogenic climate change threatens ecosystem functioning. Soil biodiversity is essential
for maintaining the health of terrestrial systems, but how climate change affects the richness …

Highly pathogenic avian influenza A (H5N1) viruses of clade 2.3. 4.4 b underwent an
explosive geographic expansion in 2021 among wild birds and domestic poultry across …

Metagenomes encode an enormous diversity of proteins, reflecting a multiplicity of functions
and activities,. Exploration of this vast sequence space has been limited to a comparative …

Background The host–microbiota interaction plays a crucial role in maintaining homeostasis
and disease susceptibility, and microbial tryptophan metabolites are potent modulators of …

Abstract SARS-CoV-2 mRNA-based vaccines are about 95% effective in preventing COVID-
19 1, 2, 3, 4, 5. The dynamics of antibody-secreting plasmablasts and germinal centre B …