Infection and the microbiome in bronchiectasis

M Mac Aogáin, AJ Dicker, P Mertsch… - European …, 2024 - publications.ersnet.org
Bronchiectasis is marked by bronchial dilatation, recurrent infections and significant
morbidity, underpinned by a complex interplay between microbial dysbiosis and immune …

Lung microbiota: Implications and interactions in chronic pulmonary diseases

J Zhou, W Hou, H Zhong, D Liu - Frontiers in Cellular and Infection …, 2024 - frontiersin.org
The lungs, as vital organs in the human body, continuously engage in gas exchange with
the external environment. The lung microbiota, a critical component in maintaining internal …

Advancements and challenges in the management of pneumonia in elderly patients with COPD

S Ocrospoma, A Anzueto… - Expert Review of …, 2024 - Taylor & Francis
ABSTRACT Introduction Chronic Obstructive Pulmonary Disease (COPD) significantly
predisposes the elderly to pneumonia, presenting a complex interplay of pulmonary …

Sputum metagenomics reveals a multidrug resistant Pseudomonas‐dominant severe asthma phenotype in an Asian population

FX Ivan, PY Tiew, TK Jaggi, KX Thng, PH Pang… - …, 2024 - Wiley Online Library
Abstract Background and Objective While the lung microbiome in severe asthma has been
studied, work has employed targeted amplicon‐based sequencing approaches without …

Correlation of Aspergillus fumigatus Sensitization with Mucus Plugging in COPD

Y Luo, J Ren, L Liang, J Qu, C Chang… - International Journal of …, 2025 - Taylor & Francis
Background Both Aspergillus fumigatus sensitization and mucus plugs are associated with
poor clinical outcomes in COPD. However, little is known about the association between …

[PDF][PDF] Of Mucus and Microbes: The Sticky Issue of Mucin-Microbiome Interactions in COPD

YJ Huang - American Journal of Respiratory and Critical Care …, 2024 - atsjournals.org
Intervening on factors that contribute to lung function decline in chronic obstructive
pulmonary disease (COPD) has long been an important goal. A subset of patients will lose …

Association of Longitudinal Albuminuria Trajectory with Lung Function Decline in the Cardia Study

H Yang, Y Yang, F Wang, L Lu, S **ao, S Zha, X Li… - papers.ssrn.com
Background: The longitudinal trajectory of albuminuria changes and their associations to
further lung function decline remain unclear. We determine the longitudinal trajectory of …