Biological membranes are tricky to investigate. They are complex in terms of molecular
composition and structure, functional over a wide range of time scales, and characterized by …

The Martini model, a coarse-grained force field for biomolecular simulations, has found a
broad range of applications since its release a decade ago. Based on a building block …

The Martini coarse-grained force field has been successfully used for simulating a wide
range of (bio) molecular systems. Recent progress in our ability to test the model against …

Computational modeling of biological systems is challenging because of the multitude of
spatial and temporal scales involved. Replacing atomistic detail with lower resolution …

The incidence of adverse effects and pathogen resistance encountered with small molecule
antibiotics is increasing. As such, there is mounting focus on immunogene therapy to …

With the rapid development of nanotechnology, nanoparticles have been widely used in
many applications such as phototherapy, cell imaging, and drug/gene delivery. A better …

Protein therapeutics are anticipated to offer significant treatment options for central nervous
system (CNS) diseases. However, the majority of proteins are unable to traverse the blood …

There is great diversity in the composition and structure of biological lipid membranes. We
are beginning to appreciate the crucial role of lipids in many cellular processes, and …

Cholesterol-phospholipid bilayers continue to be the current state of the art in membrane
models and serve as representative systems for studying the effect of cholesterol on the cell …

With the rapid development of computer power and wide availability of modelling software
computer simulations of realistic models of lipid membranes, including their interactions with …