Simple Summary Matrix stiffness is recognized as a critical factor in cancer progression.
Recent studies have shown that matrix stiffening is caused by the accumulation, contraction …

Background: Tumorigenesis is attributed to the interactions of cancer cells with the tumor
microenvironment through both biochemical cues and physical stimuli. Increased matrix …

Maintaining the balance between eliciting immune responses against foreign proteins and
tolerating self-proteins is crucial for maintenance of homeostasis. The functions of …

The interplay between extracellular matrix (ECM) stiffness and the tumor microenvironment
is increasingly recognized as a critical factor in cancer progression and the efficacy of …

Antibody–drug conjugates containing peroxide-cleavable arylboronic acid linkers are
described, which target the high levels of reactive oxygen species (ROS) in cancer. The …

The tumor biomarkers already have proven clinical value and have become an integral part
in cancer management and modern translational oncology. The tumor tissue …

Oncological diseases have become the second leading cause of death from
noncommunicable diseases worldwide and a major threat to human health. With the …

Idiopathic pulmonary fibrosis (IPF) is a progressive and often lethal interstitial lung disease
of unknown aetiology. IPF is characterised by myofibroblast activation, tissue stiffening, and …

Tumor-stromal interactions within the tumor microenvironment (TME) influence lung cancer
progression and response to therapeutic interventions, yet traditional in vitro studies fail to …

The significance of matrix stiffness in cancer development has been investigated in recent
years. The gradual elastic force the extracellular matrix imparts to cells, known as matrix …