Despite having been identified as the organism that causes tuberculosis in 1882,
Mycobacterium tuberculosis has managed to still evade our understanding of the protective …

Tuberculosis is a far-reaching, high-impact disease. It is among the top ten causes of death
worldwide caused by a single infectious agent; 1.6 million tuberculosis-related deaths were …

Tuberculosis (TB), caused by Mycobacterium tuberculosis (Mtb), is a global cause of death.
Granuloma-associated lymphoid tissue (GrALT) correlates with protection during TB, but the …

Chemokines and cytokines are critical for initiating and coordinating the organized and
sequential recruitment and activation of cells into Mycobacterium tuberculosis-infected …

Ectopic lymphoid-like structures often develop at sites of inflammation where they influence
the course of infection, autoimmune disease, cancer and transplant rejection. These …

Tuberculosis is the leading cause of death by an infectious disease worldwide. However, the
involvement of innate lymphoid cells (ILCs) in immune responses to infection with …

Tuberculosis (TB), caused by Mycobacterium tuberculosis (Mtb) latently infects
approximately one-fourth of the world's population. The immune mechanisms that govern …

Ectopic lymphoid neogenesis often occurs in the target tissues of patients with chronic
rheumatic autoimmune diseases such as rheumatoid arthritis, Sjögren syndrome and other …

T cell immunity is essential for the control of tuberculosis (TB), an important disease of the
lung, and is generally studied in humans using peripheral blood cells. Mounting evidence …

Tertiary lymphoid structures (TLS) are frequently observed in target organs of autoimmune
diseases. TLS present features of secondary lymphoid organs such as segregated T and B …