Atherosclerosis and inflammation: insights from the theory of general pathological processes

E Gusev, A Sarapultsev - International Journal of Molecular Sciences, 2023 - mdpi.com
Recent advances have greatly improved our understanding of the molecular mechanisms
behind atherosclerosis pathogenesis. However, there is still a need to systematize this data …

Immune and inflammatory mechanisms of abdominal aortic aneurysm

AC Marquez-Sanchez, EK Koltsova - Frontiers in immunology, 2022 - frontiersin.org
Abdominal aortic aneurysm (AAA) is a life-threatening cardiovascular disease. Immune-
mediated infiltration and a destruction of the aortic wall during AAA development plays …

ApoB-Specific CD4+ T Cells in Mouse and Human Atherosclerosis

T Marchini, S Hansen, D Wolf - Cells, 2021 - mdpi.com
Atherosclerosis is a chronic inflammatory condition of the arterial wall that leads to the
formation of vessel-occluding plaques within the subintimal space of middle-sized and …

The E3 ubiquitin ligase peli1 deficiency promotes atherosclerosis progression

F Burger, D Baptista, A Roth, KJ Brandt, K Miteva - Cells, 2022 - mdpi.com
Background: Atherosclerosis is a chronic inflammatory vascular disease and the main cause
of death and morbidity. Emerging evidence suggests that ubiquitination plays an important …

Cellular aspects of immunity involved in the development of atherosclerosis

K Khalaf, M Chamieh, N Welc, C Singh… - Frontiers in …, 2025 - frontiersin.org
Atherosclerosis, previously regarded as a lipid storage disease, has now been classified as
a chronic inflammatory disease. The hardening of arterial vessels characterizes …

Marginal zone B cells produce 'natural'atheroprotective IgM antibodies in a T cell–dependent manner

J Harrison, SA Newland, W Jiang… - Cardiovascular …, 2024 - academic.oup.com
Aims The adaptive immune response plays an important role in atherosclerosis. In response
to a high-fat/high-cholesterol (HF/HC) diet, marginal zone B (MZB) cells activate an …

T-Cell/B-Cell Interactions in Atherosclerosis

PW Jones, Z Mallat, M Nus - Arteriosclerosis, Thrombosis, and …, 2024 - Am Heart Assoc
Atherosclerosis is a complex inflammatory disease in which the adaptive immune response
plays an important role. While the overall impact of T and B cells in atherosclerosis is …

Identification of hub genes and transcription factors in patients with primary gout complicated with atherosclerosis

L **ao, S Lin, F Zhan - Scientific Reports, 2024 - nature.com
Evidence shows that primary gout is prone to develop to atherosclerosis, but the mechanism
of its occurrence is still not fully clarified. The aim of this study was to explore the molecular …

The Waxing, Waning, and Predictors of Humoral Responses to Vector-Based SARS-CoV-2 Vaccine in Hemodialysis Patients

CM Fu, KF Tsai, WH Kuo, CH Wu, CI Yu, HL You… - Vaccines, 2022 - mdpi.com
Hemodialysis (HD) patients are vulnerable to coronavirus disease 2019 (COVID-19) and
have a high mortality rate. We evaluated the anti-SARS-CoV-2 spike protein antibody …

Partial recovery of senescence in circulating follicular helper T cells after Dasatinib treatment

AG Talepoor, S Khosropanah, M Doroudchi - International …, 2021 - Elsevier
Cellular senescence is an irreversible arrest of cell proliferation triggered by different stimuli,
including DNA damage, telomere shortening and oncogenic stress. Senescent cells, by …