In spite of the considerable achievements in the field of regenerative medicine in the past
several decades, osteochondral defect regeneration remains a challenging issue among …

Biomedical hydrogels as sole repair matrices or combined with pre-seeded cells and
bioactive growth factors are extensively applied in tissue engineering and regenerative …

The construction of biomimetic vasculatures within the artificial tissue models or organs is
highly required for conveying nutrients, oxygen, and waste products, for improving the …

Despite tremendous advances in the field of regenerative medicine, it still remains
challenging to repair the osteochondral interface and full-thickness articular cartilage …

The osteochondral defect repair has been most extensively studied due to the rising
demand for new therapies to diseases such as osteoarthritis. Tissue engineering has been …

Tissue engineering is considered one of the most important therapeutic strategies of
regenerative medicine. The main objective of these new technologies is the development of …

Hydrogel scaffolds serve as semi synthetic or synthetic extra cellular matrix to provide an
amenable environment for cellular adherence and cellular remodeling in three dimensional …

Osteochondral defects cannot be adequately self-repaired due to the presence of the
sophisticated hierarchical structure and the lack of blood supply in cartilage. Thus, one of the …

Osteochondral (OC) repair is an extremely challenging topic due to the complex biphasic
structure and poor intrinsic regenerative capability of natural osteochondral tissue. In …

The desire and need to minimize traditional open surgeries is gearing up as it could reduce
the healthcare expenses and improve the recovery time for the patients. Minimal invasive …