Therapeutic ultrasound strategies that harness the mechanical activity of cavitation nuclei for
beneficial tissue bio-effects are actively under development. The mechanical oscillations of …

Ultrasound is a unique and exciting theranostic modality that can be used to track drug
carriers, trigger drug release and improve drug deposition with high spatial precision. In this …

Successful delivery of drugs and nanomedicine to tumors requires a functional vascular
network, extravasation across the capillary wall, penetration through the extracellular matrix …

Microbubble contrast agents and the associated imaging systems have developed over the
past 25 years, originating with manually-agitated fluids introduced for intra-coronary …

Acoustically driven bubbles produce a range of mechanical, thermal and chemical effects
that can be exploited in drug delivery applications. Significant improvements in the targeting …

This review focuses on phase‐shift perfluorocarbon nanoemulsions whose action depends
on an ultrasound‐triggered phase shift from a liquid to gas state. For drug‐loaded …

Microbubble ultrasound contrast agents have the potential to dramatically improve gene
therapy treatments by enhancing the delivery of therapeutic DNA to malignant tissue. The …

Besides the well-known and wide use of ultrasound in diagnostics, the therapeutic use of
ultrasound has recently emerged. The understanding of the action of ultrasound waves at …

Ultrasound contrast agent microbubbles have expanded the utility of biomedical ultrasound
from anatomic imaging to the assessment of microvascular blood flow characteristics and …

The interaction of nanoparticles with directed energy is a novel application in targeted drug
delivery. This chapter focuses on perfluorocarbon nanoemulsions, whose action in drug …