Functionalizing nanoparticles with biological molecules: develo** chemistries that facilitate nanotechnology

KE Sapsford, WR Algar, L Berti, KB Gemmill… - Chemical …, 2013 - ACS Publications
(5aR, 11bS)-4, 5, 5a, 6, 7, 11b-Hexahydro-2-propyl-3-thia-5-azacyclopent-1-ena [c]
phenanthrene-9, 10-diol (A-86929): a potent and selective dopamine D1 agonist that …

Polymer-based nanoparticles for oral insulin delivery: Revisited approaches

P Fonte, F Araújo, C Silva, C Pereira, S Reis… - Biotechnology …, 2015 - Elsevier
Diabetes mellitus is a high prevalence and one of the most severe and lethal diseases in the
world. Insulin is commonly used to treat diabetes in order to give patients a better life …

Novel and revisited approaches in nanoparticle systems for buccal drug delivery

AS Macedo, PM Castro, L Roque, NG Thomé… - Journal of Controlled …, 2020 - Elsevier
The buccal route is considered patient friendly due to its non-invasive nature and ease of
administration. Such delivery route has been used as an alternative for the delivery of drugs …

Oral insulin delivery: how far are we?

P Fonte, F Araújo, S Reis… - Journal of diabetes …, 2013 - journals.sagepub.com
Oral delivery of insulin may significantly improve the quality of life of diabetes patients who
routinely receive insulin by the subcutaneous route. In fact, compared with this …

[HTML][HTML] Phytosomes with Persimmon (Diospyros kaki L.) Extract: Preparation and Preliminary Demonstration of In Vivo Tolerability

R Direito, C Reis, L Roque, M Gonçalves… - Pharmaceutics, 2019 - mdpi.com
Persimmon (Diospyros kaki L.), a fruit rich in phenolic compounds (PCs), has been
considered effective in mitigating oxidative damage induced by an excess of reactive …

Recent advances in ionic liquids and nanotechnology for drug delivery

M Amaral, AB Pereiro, MM Gaspar, CP Reis - Nanomedicine, 2021 - Taylor & Francis
In drug discovery and drug development, it is estimated that around 40% of commercialized
and 90% of under-study drugs have inadequate pharmaceutical properties, severely …

Safety and toxicity issues of therapeutically used nanoparticles from the oral route

F Lotfipour, S Shahi, A Farjami, S Salatin… - BioMed Research …, 2021 - Wiley Online Library
The emerging science of nanotechnology sparked a research attention in its potential
benefits in comparison to the conventional materials used. Oral products prepared via …

Safety and toxicity concerns of orally delivered nanoparticles as drug carriers

F Araújo, N Shrestha, PL Granja… - Expert opinion on …, 2015 - Taylor & Francis
Introduction: The popularity of nanotechnology is increasing and revolutionizing extensively
the drug delivery field. Nanoparticles, as carriers for oral delivery of drugs, have been …

[HTML][HTML] Preliminary assays towards melanoma cells using phototherapy with gold-based nanomaterials

J Lopes, JMP Coelho, PMC Vieira, AS Viana… - Nanomaterials, 2020 - mdpi.com
Cancer like melanoma is a complex disease, for which standard therapies have significant
adverse side effects that in most cases are ineffective and highly unspecific. Thus, a new …

Challenges and advances in nanoparticle-based oral insulin delivery

RM Ramesan, CP Sharma - Expert Review of Medical Devices, 2009 - Taylor & Francis
For many decades, rigorous efforts have been made worldwide to develop a successful oral
insulin-delivery system, which still remains an elusive goal. However, over the past few …