[HTML][HTML] Tumor-resident microbes: the new kids on the microenvironment block

L Li, V Chandra, F McAllister - Trends in cancer, 2024 - cell.com
Tumor-resident microbes (TRM) are an integral component of the tumor microenvironment
(TME). TRM can influence tumor growth, distant dissemination, and response to therapies by …

Biological function and clinical application prospect of tsRNAs in digestive system biology and pathology

J Du, T Huang, Z Zheng, S Fang, H Deng… - Cell Communication and …, 2023 - Springer
Abstract tsRNAs are small non-coding RNAs originating from tRNA that play important roles
in a variety of physiological activities such as RNA silencing, ribosome biogenesis …

Organophosphorus mineralizing-Streptomyces species underpins uranate immobilization and phosphorus availability in uranium tailings

N Hu, F **ao, D Zhang, R Hu, R **ong, W Lv… - Journal of Hazardous …, 2024 - Elsevier
Phosphate-solubilizing bacteria (PSB) are important but often overlooked regulators of
uranium (U) cycling in soil. However, the impact of PSB on uranate fixation coupled with the …

[HTML][HTML] tsRNA modifications: an emerging layer of biological regulation in disease

Y Liang, D Ji, X Ying, R Ma, W Ji - Journal of Advanced Research, 2024 - Elsevier
Abstract Background Transfer RNA (tRNA)-derived small RNA (tsRNA) represents an
important and increasingly valued type of small non-coding RNA (sncRNA). The …

Diverse plant RNAs coat Arabidopsis leaves and are distinct from apoplastic RNAs

ML Borniego, M Singla-Rastogi, P Baldrich… - Proceedings of the …, 2025 - pnas.org
Transgenic expression of a double-stranded RNA in plants can induce silencing of
homologous mRNAs in fungal pathogens. Although such host-induced gene silencing is …

Targeted elimination of Fusobacterium nucleatum alleviates periodontitis

N Yakar, O Unlu, L Cen, H Hasturk, T Chen… - Journal of Oral …, 2024 - Taylor & Francis
Background Fusobacterium nucleatum, a pathobiont in periodontal disease, contributes to
alveolar bone destruction. We assessed the efficacy of a new targeted antimicrobial, FP-100 …

Screening inhibitors against the Ef-Tu of Fusobacterium nucleatum: a docking, ADMET and PBPK assessment study

A Alzamami, NA Alturki, K Khan, Z Basharat… - Molecular Diversity, 2024 - Springer
The oral pathogen Fusobacterium nucleatum has recently been associated with an elevated
risk of colorectal cancer (CRC), endometrial metastasis, chemoresistance, inflammation …

tRNA-derived small RNAs: their role in the mechanisms, biomarkers, and therapeutic strategies of colorectal cancer

B Zhang, Y Pan, Z Li, K Hu - Journal of Translational Medicine, 2025 - Springer
Colorectal cancer (CRC) is the third most prevalent malignancy and the second leading
cause of cancer-related mortality worldwide, with an increasing shift towards younger age of …

An antisense oligomer conjugate with unpredicted bactericidal activity against Fusobacterium nucleatum

V Cosi, J Jung, L Popella, F Ponath, C Ghosh… - bioRxiv, 2025 - biorxiv.org
Fusobacteria are commensal members of the oral microbiome that can spread from their
primary niche and colonize distal sites in the human body. Their enrichment in colorectal …

Identification of P-type ATPase as a bacterial transporter for host-derived small RNA

PT Dong, M Yang, L Cen, P Zhou, D Xu, P **ong, C Wu… - bioRxiv, 2024 - biorxiv.org
Host-derived small RNAs represent a finely tuned host response to maintain the host-
microbial homeostasis. Among these, an emerging class known as transfer RNA-derived …