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[HTML][HTML] Tumor-resident microbes: the new kids on the microenvironment block
Tumor-resident microbes (TRM) are an integral component of the tumor microenvironment
(TME). TRM can influence tumor growth, distant dissemination, and response to therapies by …
(TME). TRM can influence tumor growth, distant dissemination, and response to therapies by …
Biological function and clinical application prospect of tsRNAs in digestive system biology and pathology
J Du, T Huang, Z Zheng, S Fang, H Deng… - Cell Communication and …, 2023 - Springer
Abstract tsRNAs are small non-coding RNAs originating from tRNA that play important roles
in a variety of physiological activities such as RNA silencing, ribosome biogenesis …
in a variety of physiological activities such as RNA silencing, ribosome biogenesis …
Organophosphorus mineralizing-Streptomyces species underpins uranate immobilization and phosphorus availability in uranium tailings
N Hu, F **ao, D Zhang, R Hu, R **ong, W Lv… - Journal of Hazardous …, 2024 - Elsevier
Phosphate-solubilizing bacteria (PSB) are important but often overlooked regulators of
uranium (U) cycling in soil. However, the impact of PSB on uranate fixation coupled with the …
uranium (U) cycling in soil. However, the impact of PSB on uranate fixation coupled with the …
[HTML][HTML] tsRNA modifications: an emerging layer of biological regulation in disease
Y Liang, D Ji, X Ying, R Ma, W Ji - Journal of Advanced Research, 2024 - Elsevier
Abstract Background Transfer RNA (tRNA)-derived small RNA (tsRNA) represents an
important and increasingly valued type of small non-coding RNA (sncRNA). The …
important and increasingly valued type of small non-coding RNA (sncRNA). The …
Diverse plant RNAs coat Arabidopsis leaves and are distinct from apoplastic RNAs
Transgenic expression of a double-stranded RNA in plants can induce silencing of
homologous mRNAs in fungal pathogens. Although such host-induced gene silencing is …
homologous mRNAs in fungal pathogens. Although such host-induced gene silencing is …
Targeted elimination of Fusobacterium nucleatum alleviates periodontitis
Background Fusobacterium nucleatum, a pathobiont in periodontal disease, contributes to
alveolar bone destruction. We assessed the efficacy of a new targeted antimicrobial, FP-100 …
alveolar bone destruction. We assessed the efficacy of a new targeted antimicrobial, FP-100 …
Screening inhibitors against the Ef-Tu of Fusobacterium nucleatum: a docking, ADMET and PBPK assessment study
A Alzamami, NA Alturki, K Khan, Z Basharat… - Molecular Diversity, 2024 - Springer
The oral pathogen Fusobacterium nucleatum has recently been associated with an elevated
risk of colorectal cancer (CRC), endometrial metastasis, chemoresistance, inflammation …
risk of colorectal cancer (CRC), endometrial metastasis, chemoresistance, inflammation …
tRNA-derived small RNAs: their role in the mechanisms, biomarkers, and therapeutic strategies of colorectal cancer
B Zhang, Y Pan, Z Li, K Hu - Journal of Translational Medicine, 2025 - Springer
Colorectal cancer (CRC) is the third most prevalent malignancy and the second leading
cause of cancer-related mortality worldwide, with an increasing shift towards younger age of …
cause of cancer-related mortality worldwide, with an increasing shift towards younger age of …
An antisense oligomer conjugate with unpredicted bactericidal activity against Fusobacterium nucleatum
Fusobacteria are commensal members of the oral microbiome that can spread from their
primary niche and colonize distal sites in the human body. Their enrichment in colorectal …
primary niche and colonize distal sites in the human body. Their enrichment in colorectal …
Identification of P-type ATPase as a bacterial transporter for host-derived small RNA
Host-derived small RNAs represent a finely tuned host response to maintain the host-
microbial homeostasis. Among these, an emerging class known as transfer RNA-derived …
microbial homeostasis. Among these, an emerging class known as transfer RNA-derived …