Nanomaterial-based therapeutics for antibiotic-resistant bacterial infections

JMV Makabenta, A Nabawy, CH Li… - Nature Reviews …, 2021 - nature.com
Antibiotic-resistant bacterial infections arising from acquired resistance and/or through
biofilm formation necessitate the development of innovative 'outside of the box'therapeutics …

Infection microenvironment-related antibacterial nanotherapeutic strategies

Z Wang, X Liu, Y Duan, Y Huang - Biomaterials, 2022 - Elsevier
The emergence and spread of antibiotic resistance is one of the biggest challenges in public
health. There is an urgent need to discover novel agents against the occurrence of multidrug …

Thermal atomization of platinum nanoparticles into single atoms: An effective strategy for engineering high-performance nanozymes

Y Chen, P Wang, H Hao, J Hong, H Li, S Ji… - Journal of the …, 2021 - ACS Publications
Although great progress has been made in artificial enzyme engineering, their catalytic
performance is far from satisfactory as alternatives of natural enzymes. Here, we report a …

Janus nanoparticles targeting extracellular polymeric substance achieve flexible elimination of drug-resistant biofilms

Z Liu, K Guo, L Yan, K Zhang, Y Wang, X Ding… - Nature …, 2023 - nature.com
Safe and efficient antibacterial materials are urgently needed to combat drug-resistant
bacteria and biofilm-associated infections. The rational design of nanoparticles for flexible …

An overview of the use of nanozymes in antibacterial applications

L Mei, S Zhu, Y Liu, W Yin, Z Gu, Y Zhao - Chemical Engineering Journal, 2021 - Elsevier
Topics of bacterial resistance have attracted remarkable scientific interests. Bacterial
infection-related diseases are major public safety issues that lead to millions of deaths …

[HTML][HTML] Repurposing ferumoxytol: Diagnostic and therapeutic applications of an FDA-approved nanoparticle

Y Huang, JC Hsu, H Koo, DP Cormode - Theranostics, 2022 - ncbi.nlm.nih.gov
Ferumoxytol is an intravenous iron oxide nanoparticle formulation that has been approved
by the US Food and Drug Administration (FDA) for treating anemia in patients with chronic …

Nanozymes for regenerative medicine

X Mou, Q Wu, Z Zhang, Y Liu, J Zhang, C Zhang… - Small …, 2022 - Wiley Online Library
Nanozymes refer to nanomaterials that catalyze enzyme substrates into products under
relevant physiological conditions following enzyme kinetics. Compared to natural enzymes …

Nanocatalytic medicine

B Yang, Y Chen, J Shi - Advanced materials, 2019 - Wiley Online Library
Catalysis and medicine are often considered as two independent research fields with their
own respective scientific phenomena. Promoted by recent advances in nanochemistry, large …

Nanotechnology's frontier in combatting infectious and inflammatory diseases: prevention and treatment

Y Huang, X Guo, Y Wu, X Chen, L Feng, N **e… - … and Targeted Therapy, 2024 - nature.com
Inflammation-associated diseases encompass a range of infectious diseases and non-
infectious inflammatory diseases, which continuously pose one of the most serious threats to …

Stimuli-activable metal-bearing nanomaterials and precise on-demand antibacterial strategies

Y Zhong, XT Zheng, S Zhao, X Su, XJ Loh - ACS nano, 2022 - ACS Publications
Bacterial infections remain the leading cause of death worldwide today. The emergence of
antibiotic resistance has urged the development of alternative antibacterial technologies to …