Biological underpinnings for lifelong learning machines
Biological organisms learn from interactions with their environment throughout their lifetime.
For artificial systems to successfully act and adapt in the real world, it is desirable to similarly …
For artificial systems to successfully act and adapt in the real world, it is desirable to similarly …
Astrocyte crosstalk in CNS inflammation
Astrocytes control multiple processes in the nervous system in health and disease. It is now
clear that specific astrocyte subsets or activation states are associated with specific genomic …
clear that specific astrocyte subsets or activation states are associated with specific genomic …
Neuronal wiring diagram of an adult brain
Connections between neurons can be mapped by acquiring and analysing electron
microscopic brain images. In recent years, this approach has been applied to chunks of …
microscopic brain images. In recent years, this approach has been applied to chunks of …
A multimodal cell census and atlas of the mammalian primary motor cortex
Principal manuscript editors, Analysis coordination… - Nature, 2021 - nature.com
Here we report the generation of a multimodal cell census and atlas of the mammalian
primary motor cortex as the initial product of the BRAIN Initiative Cell Census Network …
primary motor cortex as the initial product of the BRAIN Initiative Cell Census Network …
[HTML][HTML] Spatially resolved cell atlas of the mouse primary motor cortex by MERFISH
A mammalian brain is composed of numerous cell types organized in an intricate manner to
form functional neural circuits. Single-cell RNA sequencing allows systematic identification …
form functional neural circuits. Single-cell RNA sequencing allows systematic identification …
Morphological diversity of single neurons in molecularly defined cell types
H Peng, P ** reveals that engrams for a single memory are distributed across multiple brain regions
Neuronal ensembles that hold specific memory (memory engrams) have been identified in
the hippocampus, amygdala, or cortex. However, it has been hypothesized that engrams of …
the hippocampus, amygdala, or cortex. However, it has been hypothesized that engrams of …
Single-neuron projectome of mouse prefrontal cortex
Prefrontal cortex (PFC) is the cognitive center that integrates and regulates global brain
activity. However, the whole-brain organization of PFC axon projections remains poorly …
activity. However, the whole-brain organization of PFC axon projections remains poorly …
A unifying perspective on neural manifolds and circuits for cognition
Two different perspectives have informed efforts to explain the link between the brain and
behaviour. One approach seeks to identify neural circuit elements that carry out specific …
behaviour. One approach seeks to identify neural circuit elements that carry out specific …
The Allen mouse brain common coordinate framework: a 3D reference atlas
Recent large-scale collaborations are generating major surveys of cell types and
connections in the mouse brain, collecting large amounts of data across modalities, spatial …
connections in the mouse brain, collecting large amounts of data across modalities, spatial …