Status and prospects of genome‐wide association studies in plants
Genome‐wide association studies (GWAS) have developed into a powerful and ubiquitous
tool for the investigation of complex traits. In large part, this was fueled by advances in …
tool for the investigation of complex traits. In large part, this was fueled by advances in …
Salt stress under the scalpel–dissecting the genetics of salt tolerance
Salt stress limits the productivity of crops grown under saline conditions, leading to
substantial losses of yield in saline soils and under brackish and saline irrigation. Salt …
substantial losses of yield in saline soils and under brackish and saline irrigation. Salt …
A generalized linear mixed model association tool for biobank-scale data
Compared with linear mixed model-based genome-wide association (GWA) methods,
generalized linear mixed model (GLMM)-based methods have better statistical properties …
generalized linear mixed model (GLMM)-based methods have better statistical properties …
A transcriptional regulator that boosts grain yields and shortens the growth duration of rice
S Wei, X Li, Z Lu, H Zhang, X Ye, Y Zhou, J Li, Y Yan… - Science, 2022 - science.org
Complex biological processes such as plant growth and development are often under the
control of transcription factors that regulate the expression of large sets of genes and …
control of transcription factors that regulate the expression of large sets of genes and …
GAPIT version 3: boosting power and accuracy for genomic association and prediction
Genome-wide association study (GWAS) and genomic prediction/selection (GP/GS) are the
two essential enterprises in genomic research. Due to the great magnitude and complexity …
two essential enterprises in genomic research. Due to the great magnitude and complexity …
rMVP: a memory-efficient, visualization-enhanced, and parallel-accelerated tool for genome-wide association study
Along with the development of high-throughput sequencing technologies, both sample size
and SNP number are increasing rapidly in genome-wide association studies (GWAS), and …
and SNP number are increasing rapidly in genome-wide association studies (GWAS), and …
Computationally efficient whole-genome regression for quantitative and binary traits
Genome-wide association analysis of cohorts with thousands of phenotypes is
computationally expensive, particularly when accounting for sample relatedness or …
computationally expensive, particularly when accounting for sample relatedness or …
Efficiently controlling for case-control imbalance and sample relatedness in large-scale genetic association studies
In genome-wide association studies (GWAS) for thousands of phenotypes in large biobanks,
most binary traits have substantially fewer cases than controls. Both of the widely used …
most binary traits have substantially fewer cases than controls. Both of the widely used …
A resource-efficient tool for mixed model association analysis of large-scale data
The genome-wide association study (GWAS) has been widely used as an experimental
design to detect associations between genetic variants and a phenotype. Two major …
design to detect associations between genetic variants and a phenotype. Two major …
Genome-wide dissection of changes in maize root system architecture during modern breeding
W Ren, L Zhao, J Liang, L Wang, L Chen, P Li, Z Liu… - Nature Plants, 2022 - nature.com
Appropriate root system architecture (RSA) can improve maize yields in densely planted
fields, but little is known about its genetic basis in maize. Here we performed root …
fields, but little is known about its genetic basis in maize. Here we performed root …