Status and prospects of genome‐wide association studies in plants

L Tibbs Cortes, Z Zhang, J Yu - The plant genome, 2021 - Wiley Online Library
Genome‐wide association studies (GWAS) have developed into a powerful and ubiquitous
tool for the investigation of complex traits. In large part, this was fueled by advances in …

[PDF][PDF] Genome-wide association study of complex traits in maize detects genomic regions and genes for increasing grain yield and grain quality

Y Dwiningsih, J Al-Kahtani - Advance Sustainable Science …, 2022 - academia.edu
This review describes the current status of genome-wide association study (GWAS) of the
major crops in maize (Zea mays L.) concentrate on performing association map** as a …

A transcriptional regulator that boosts grain yields and shortens the growth duration of rice

S Wei, X Li, Z Lu, H Zhang, X Ye, Y Zhou, J Li, Y Yan… - Science, 2022 - science.org
Complex biological processes such as plant growth and development are often under the
control of transcription factors that regulate the expression of large sets of genes and …

A generalized linear mixed model association tool for biobank-scale data

L Jiang, Z Zheng, H Fang, J Yang - Nature genetics, 2021 - nature.com
Compared with linear mixed model-based genome-wide association (GWA) methods,
generalized linear mixed model (GLMM)-based methods have better statistical properties …

GAPIT version 3: boosting power and accuracy for genomic association and prediction

J Wang, Z Zhang - Genomics, proteomics & bioinformatics, 2021 - academic.oup.com
Genome-wide association study (GWAS) and genomic prediction/selection (GP/GS) are the
two essential enterprises in genomic research. Due to the great magnitude and complexity …

rMVP: a memory-efficient, visualization-enhanced, and parallel-accelerated tool for genome-wide association study

L Yin, H Zhang, Z Tang, J Xu, D Yin… - Genomics …, 2021 - academic.oup.com
Along with the development of high-throughput sequencing technologies, both sample size
and SNP number are increasing rapidly in genome-wide association studies (GWAS), and …

Computationally efficient whole-genome regression for quantitative and binary traits

J Mbatchou, L Barnard, J Backman, A Marcketta… - Nature …, 2021 - nature.com
Genome-wide association analysis of cohorts with thousands of phenotypes is
computationally expensive, particularly when accounting for sample relatedness or …

Variation in TaSPL6-D confers salinity tolerance in bread wheat by activating TaHKT1;5-D while preserving yield-related traits

M Wang, J Cheng, J Wu, J Chen, D Liu, C Wang… - Nature Genetics, 2024 - nature.com
Na+ exclusion from above-ground tissues via the Na+-selective transporter HKT1; 5 is a
major salt-tolerance mechanism in crops. Using the expression genome-wide association …

A resource-efficient tool for mixed model association analysis of large-scale data

L Jiang, Z Zheng, T Qi, KE Kemper, NR Wray… - Nature …, 2019 - nature.com
The genome-wide association study (GWAS) has been widely used as an experimental
design to detect associations between genetic variants and a phenotype. Two major …

CaeNDR, the Caenorhabditis Natural Diversity Resource

TA Crombie, R McKeown, ND Moya… - Nucleic Acids …, 2024 - academic.oup.com
Studies of model organisms have provided important insights into how natural genetic
differences shape trait variation. These discoveries are driven by the growing availability of …