Human tissues must be elastic, much like other materials that work under continuous loads
without losing functionality. The elasticity of tissues is provided by elastin, a unique protein of …

Aortic dissection (AD) is a condition of the main artery of the human body, resulting in the
formation of a new flow channel, or false lumen. The disease is usually diagnosed with a …

Vascular remodeling is a common pathological hallmark of many cardiovascular diseases.
Vascular smooth muscle cells (VSMCs) are the predominant cell type lining the tunica media …

Aortic dissection continues to be responsible for significant morbidity and mortality, although
recent advances in medical data assimilation and in experimental and in silico models have …

Cardiovascular diseases are the leading cause of death worldwide and include, among
others, critical conditions of the aortic wall. Importantly, such critical conditions require …

Abstract Background and Aims Stanford type A aortic dissection (AD) is a degenerative
aortic remodelling disease marked by an exceedingly high mortality without effective …

Cardiovascular diseases represent a complex group of clinical syndromes caused by a
variety of interacting pathological factors. They include the most extensive disease …

The ascending thoracic aortic aneurysm (ATAA) is a permanent dilatation of the vessel with
a high risk of adverse events, and shows heterogeneous properties. To investigate regional …

Soft biological tissues are natural biomaterials with structures that have evolved to perform
physiological functions, for example, conferring elasticity while preserving the mechanical …

Disease of the aortic arch, descending thoracic, or thoracoabdominal aorta necessitates
dedicated expertise across medical, endovascular, and surgical specialties. Cardiologists …