Drug resistance in nontuberculous mycobacteria: mechanisms and models

S Saxena, HP Spaink, G Forn-Cuní - Biology, 2021 - mdpi.com
Simple Summary Recently, there has been a considerable rise in infections caused by
nontuberculous mycobacteria (NTM). These mycobacteria, which comprise a large and …

High mortality in patients with Mycobacterium avium complex lung disease: a systematic review

R Diel, M Lipman, W Hoefsloot - BMC infectious diseases, 2018 - Springer
Background The incidence of nontuberculous mycobacterial (NTM) pulmonary disease
caused by Mycobacterium avium complex (MAC) in apparently immune-competent people is …

BACES score for predicting mortality in nontuberculous mycobacterial pulmonary disease

HJ Kim, N Kwak, H Hong, N Kang, Y Im… - American Journal of …, 2021 - atsjournals.org
Rationale: Because the prognosis of nontuberculous mycobacterial pulmonary disease
varies, a scoring system predicting mortality is needed. Objectives: We aimed to develop a …

Mycobacterium abscessus smooth and rough morphotypes form antimicrobial-tolerant biofilm phenotypes but are killed by acetic acid

G Clary, SJ Sasindran, N Nesbitt, L Mason… - Antimicrobial agents …, 2018 - Am Soc Microbiol
Mycobacterium abscessus has emerged as an important pathogen in people with chronic
inflammatory lung diseases such as cystic fibrosis, and recent reports suggest that it may be …

Five-year outcomes among US bronchiectasis and NTM research registry patients

TR Aksamit, N Locantore, D Addrizzo-Harris… - American journal of …, 2024 - atsjournals.org
Rationale: Nontuberculous mycobacteria (NTM) are prevalent among patients with
bronchiectasis. However, the long-term natural history of patients with NTM and …

Quorum sensing as antivirulence target in cystic fibrosis pathogens

VC Scoffone, G Trespidi, LR Chiarelli… - International journal of …, 2019 - mdpi.com
Cystic fibrosis (CF) is an autosomal recessive genetic disorder which leads to the secretion
of a viscous mucus layer on the respiratory epithelium that facilitates colonization by various …

Pulmonary disease by non-tuberculous mycobacteria–clinical management, unmet needs and future perspectives

LO Larsson, E Polverino, W Hoefsloot… - Expert review of …, 2017 - Taylor & Francis
Introduction: The number of patients with pulmonary disease caused by non-tuberculous
mycobacteria (NTM) is increasing globally. Poor resistance against infections, for example …

[HTML][HTML] Pulmonary nontuberculous mycobacteria–associated deaths, Ontario, Canada, 2001–2013

TK Marras, MA Campitelli, H Lu, H Chung… - Emerging infectious …, 2017 - ncbi.nlm.nih.gov
Survival implications of nontuberculous mycobacterial pulmonary disease (NTM-PD) and
NTM pulmonary isolation without disease (NTM-PI) are unclear. To study deaths associated …

Meeting the challenges of NTM-PD from the perspective of the organism and the disease process: innovations in drug development and delivery

R van der Laan, A Snabilié, M Obradovic - Respiratory Research, 2022 - Springer
Non-tuberculous mycobacterial pulmonary disease (NTM-PD) poses a substantial patient,
healthcare, and economic burden. Managing NTM-PD remains challenging, and factors …

Usefulness of the BACES score in nontuberculous mycobacterial pulmonary disease for various clinical outcomes

HJ Kim, MJ Song, BS Kwon, YW Kim, SY Lim… - Scientific Reports, 2023 - nature.com
A uniform prognostic marker is needed for nontuberculous mycobacterial pulmonary
disease (NTM-PD) due to the diverse clinical course. We aimed to seek the utility of the …