The mitochondrion is an organelle that plays a vital role in the regulation of hepatic cellular
redox, lipid metabolism, and cell death. Mitochondrial dysfunction is associated with both …

Nonalcoholic fatty liver disease (NAFLD) is a worldwide rising challenge because of hepatic,
but also extrahepatic, complications. Thyroid hormones are master regulators of energy and …

The liver is an important metabolic and detoxification organ and hence demands a large
amount of energy, which is mainly produced by the mitochondria. Liver tissues of patients …

The mitochondrion is an organelle that plays a vital role in energy production, cytoplasmic
protein degradation and cell death. Mitophagy is an autophagic procedure that specifically …

Thyroid hormone receptor β1 (THRB1) and estrogen-related receptor α (ESRRA; also
known as ERRα) both play important roles in mitochondrial activity. To understand their …

Autophagy is a catabolic process involving vacuolar sequestration of intracellular
components and their targeting to lysosomes for degradation, thus supporting nutrient …

Much is known, but there is also much more to discover, about the actions that thyroid
hormones (TH) exert on metabolism. Indeed, despite the fact that thyroid hormones are …

Hepatitis B virus (HBV) is one of predisposing factors for hepatocellular carcinoma (HCC).
The role of HBV x protein (HBx) in mediating the induction and maintenance of cancer …

The liver is controlled by several metabolic hormones, including thyroid hormone, and
characteristically displays high lysosomal activity as well as metabolic stress-triggered …

The energy homeostasis of the organism is orchestrated by a complex interplay of energy
substrate shuttling, breakdown, storage, and distribution. Many of these processes are …