2023 ESC Guidelines for the management of cardiovascular disease in patients with diabetes: Developed by the task force on the management of cardiovascular …

N Marx, M Federici, K Schütt… - European heart …, 2023 - academic.oup.com
• The specific situation of the patient. Unless otherwise provided for by national regulations,
off-label use of medication should be limited to situations where it is in the patient's interest …

Mendelian randomization

E Sanderson, MM Glymour, MV Holmes… - Nature Reviews …, 2022 - nature.com
Mendelian randomization (MR) is a term that applies to the use of genetic variation to
address causal questions about how modifiable exposures influence different outcomes …

[HTML][HTML] Population-level risks of alcohol consumption by amount, geography, age, sex, and year: a systematic analysis for the Global Burden of Disease Study 2020

D Bryazka, MB Reitsma, MG Griswold, KH Abate… - The Lancet, 2022 - thelancet.com
Background The health risks associated with moderate alcohol consumption continue to be
debated. Small amounts of alcohol might lower the risk of some health outcomes but …

2021 ESC Guidelines on cardiovascular disease prevention in clinical practice: Developed by the Task Force for cardiovascular disease prevention in clinical practice …

FLJ Visseren, F Mach, YM Smulders… - European heart …, 2021 - academic.oup.com
Atherosclerotic cardiovascular (CV) disease (ASCVD) incidence and mortality rates are
declining in many countries in Europe, but it is still a major cause of morbidity and mortality …

Mendelian randomization: concepts and scope

RC Richmond, GD Smith - Cold Spring …, 2022 - perspectivesinmedicine.cshlp.org
Mendelian randomization (MR) is a method of studying the causal effects of modifiable
exposures (ie, potential risk factors) on health, social, and economic outcomes using genetic …

2023 ESC guidelines for the management of acute coronary syndromes: developed by the task force on the management of acute coronary syndromes of the …

RA Byrne, X Rossello, JJ Coughlan… - … Heart Journal: Acute …, 2024 - academic.oup.com
2023 ESC Guidelines for the management of acute coronary syndromes Page 1 2023 ESC
Guidelines for the management of acute coronary syndromes Developed by the task force on …

Association of habitual alcohol intake with risk of cardiovascular disease

KJ Biddinger, CA Emdin, ME Haas, M Wang… - JAMA network …, 2022 - jamanetwork.com
Importance Observational studies have consistently proposed cardiovascular benefits
associated with light alcohol consumption, while recent genetic analyses (ie, mendelian …

Mendelian randomization for cardiovascular diseases: principles and applications

SC Larsson, AS Butterworth… - European heart journal, 2023 - academic.oup.com
Large-scale genome-wide association studies conducted over the last decade have
uncovered numerous genetic variants associated with cardiometabolic traits and risk factors …

The global epidemiology of hypertension

KT Mills, A Stefanescu, J He - Nature Reviews Nephrology, 2020 - nature.com
Hypertension is the leading cause of cardiovascular disease and premature death
worldwide. Owing to the widespread use of antihypertensive medications, global mean …

Guidelines for performing Mendelian randomization investigations: update for summer 2023

S Burgess, GD Smith, NM Davies… - Wellcome open …, 2023 - pmc.ncbi.nlm.nih.gov
This paper provides guidelines for performing Mendelian randomization investigations. It is
aimed at practitioners seeking to undertake analyses and write up their findings, and at …