Group 2 innate lymphoid cells in airway diseases
A Kato - Chest, 2019 - Elsevier
Group 2 innate lymphoid cells (ILC2s) are increasingly recognized as a key controller of type
2 inflammation, and are well known to be highly elevated in human airway type 2 …
2 inflammation, and are well known to be highly elevated in human airway type 2 …
The immune landscape of thyroid cancer in the context of immune checkpoint inhibition
G Varricchi, S Loffredo, G Marone, L Modestino… - International Journal of …, 2019 - mdpi.com
Immune cells play critical roles in tumor prevention as well as initiation and progression.
However, immune-resistant cancer cells can evade the immune system and proceed to form …
However, immune-resistant cancer cells can evade the immune system and proceed to form …
Two‐year results of tapered dupilumab for CRSwNP demonstrates enduring efficacy established in the first 6 months
RJL van der Lans, JJ Otten, GFJPM Adriaensen… - Allergy, 2023 - Wiley Online Library
Background Dupilumab is an anti‐T2‐inflammatory biological registered for chronic
rhinosinusitis (CRS) with nasal polyps (CRSwNP), indicated by integrated CRS‐care …
rhinosinusitis (CRS) with nasal polyps (CRSwNP), indicated by integrated CRS‐care …
BATF promotes group 2 innate lymphoid cell–mediated lung tissue protection during acute respiratory virus infection
Activated group 2 innate lymphoid cells (ILC2s) accumulate and promote inflammatory
resolution and tissue repair in host defense against acute respiratory viral infections …
resolution and tissue repair in host defense against acute respiratory viral infections …
Polychromic reporter mice reveal unappreciated innate lymphoid cell progenitor heterogeneity and elusive ILC3 progenitors in bone marrow
Innate lymphoid cells (ILCs) play strategic roles in tissue homeostasis and immunity. ILCs
arise from lymphoid progenitors undergoing lineage restriction and the development of …
arise from lymphoid progenitors undergoing lineage restriction and the development of …
Single-cell chromatin accessibility and transposable element landscapes reveal shared features of tissue-residing immune cells
M Simon, P Stüve, L Schmidleithner, S Bittner… - Immunity, 2024 - cell.com
Tissue adaptation is required for regulatory T (Treg) cell function within organs. Whether this
program shares aspects with other tissue-localized immune populations is unclear. Here, we …
program shares aspects with other tissue-localized immune populations is unclear. Here, we …
Human CD127 negative ILC2s show immunological memory
ILC2s are key players in type 2 immunity and contribute to maintaining homeostasis. ILC2s
are also implicated in the development of type 2 inflammation–mediated chronic disorders …
are also implicated in the development of type 2 inflammation–mediated chronic disorders …
A pathogenic integrated view explaining the different endotypes of asthma and allergic disorders
The inflammation of allergic diseases is characterized by a complex interaction between
type 2 and type 3 immune responses, explaining clinical symptoms and histopathological …
type 2 and type 3 immune responses, explaining clinical symptoms and histopathological …
[HTML][HTML] Pulmonary group 2 innate lymphoid cells: surprises and challenges
Group 2 innate lymphoid cells (ILC2s) are a recently described subset of innate lymphocytes
with important immune and homeostatic functions at multiple tissue sites, especially the …
with important immune and homeostatic functions at multiple tissue sites, especially the …
Emerging insights into the impact of air pollution on immune-mediated asthma pathogenesis
Abstract Purpose of Review Increases in ambient levels of air pollutants have been linked to
lung inflammation and remodeling, processes that lead to the development and …
lung inflammation and remodeling, processes that lead to the development and …