Genetic Predisposition to Colorectal Cancer: How Many and Which Genes to Test?
Colorectal cancer is one of the most common tumors, and genetic predisposition is one of
the key risk factors in the development of this malignancy. Lynch syndrome and familial …
the key risk factors in the development of this malignancy. Lynch syndrome and familial …
[HTML][HTML] Lynch syndrome
Lynch Syndrome - Abstract - Europe PMC Sign in | Create an account https://orcid.org Europe
PMC Menu About Tools Developers Help Contact us Helpdesk Feedback Twitter Blog Tech …
PMC Menu About Tools Developers Help Contact us Helpdesk Feedback Twitter Blog Tech …
From APC to the genetics of hereditary and familial colon cancer syndromes
AP Olkinuora, PT Peltomäki, LA Aaltonen… - Human Molecular …, 2021 - academic.oup.com
Hereditary colorectal cancer (CRC) syndromes attributable to high penetrance mutations
represent 9–26% of young-onset CRC cases. The clinical significance of many of these …
represent 9–26% of young-onset CRC cases. The clinical significance of many of these …
Significance of rare variants in genes involved in the pathogenesis of Lynch syndrome
R Liccardo, M Lambiase, A Nolano… - International …, 2022 - spandidos-publications.com
The molecular characterization of patients with Lynch syndrome (LS) involves germline
testing to detect a deleterious mutation in one of the genes of the mismatch repair (MMR) …
testing to detect a deleterious mutation in one of the genes of the mismatch repair (MMR) …
[HTML][HTML] Current status of the genetic susceptibility in attenuated adenomatous polyposis
V Lorca, P Garre - World Journal of Gastrointestinal Oncology, 2019 - ncbi.nlm.nih.gov
Adenomatous polyposis (AP) is classified according to cumulative adenoma number in
classical AP (CAP) and attenuated AP (AAP). Genetic susceptibility is the major risk factor in …
classical AP (CAP) and attenuated AP (AAP). Genetic susceptibility is the major risk factor in …
[HTML][HTML] Attenuated adenomatous polyposis with MSH6 variation: Two case reports
GW Ha, MR Lee, AR Ahn, MJ Chung, KM Kim - Medicine, 2024 - journals.lww.com
Interventions: The 2 received genetic consultation; and, for follow-up purposes, both patients
agreed to be tested for an underlying genetic condition through next generation sequencing …
agreed to be tested for an underlying genetic condition through next generation sequencing …
Evaluating the role of MLH3 p.Ser1188Ter variant in inherited breast cancer predisposition
S Koivuluoma, R Winqvist, R Keski-Filppula… - Genetics in …, 2020 - nature.com
Germline loss-of-function variants in mismatch repair (MMR) genes elevate risk for specific
cancer types, especially colorectal, endometrial, and gastric carcinomas. 1-3 Whether MMR …
cancer types, especially colorectal, endometrial, and gastric carcinomas. 1-3 Whether MMR …
Genetic Predisposition to Colorectal Cancer: How Many and Which Genes to Test
Colorectal cancer is one of the most common tumors, and genetic predisposition is one of
the key risk factors in the development of this malignancy. Lynch syndrome and familial …
the key risk factors in the development of this malignancy. Lynch syndrome and familial …
Estudio de la susceptibilidad genética en la poliposis adenomatosa atenuada
V Lorca Castellanos - 2024 - docta.ucm.es
Me gustaría empezar este apartado nombrando a la persona que me ha dado la
oportunidad de crecer y formarme científica, profesional y personalmente en el campo de la …
oportunidad de crecer y formarme científica, profesional y personalmente en el campo de la …
[PDF][PDF] Germline variants in the mismatch repair genes: Detection and phenotype
M Suerink - Oncology, 2016 - scholarlypublications …
Constitutional mismatch repair deficiency (CMMRD) is a rare childhood cancer
predisposition syndrome caused by biallelic germline mutations in one of four mismatch …
predisposition syndrome caused by biallelic germline mutations in one of four mismatch …