The determinants regulating Toxoplasma gondii bradyzoite development

M Pan, CC Ge, YM Fan, QW **, B Shen… - Frontiers in …, 2022 - frontiersin.org
Toxoplasma gondii is an obligate intracellular zoonotic pathogen capable of infecting almost
all cells of warm-blooded vertebrates. In intermediate hosts, this parasite reproduces …

Metabolic changes in Toxoplasma gondii-infected host cells measured by autofluorescence imaging

GM Gallego-López, E Contreras Guzman, DE Desa… - Mbio, 2024 - journals.asm.org
Toxoplasma gondii, the causative agent of toxoplasmosis, is an obligate intracellular
parasite that infects warm-blooded vertebrates across the world. In humans, seropositivity …

Toxoplasma protein export and effector function

S Seizova, A Ferrel, J Boothroyd, CJ Tonkin - Nature Microbiology, 2024 - nature.com
Toxoplasma gondii is a single-celled eukaryotic parasite with a considerable host range that
must invade the cells of warm-blooded hosts to survive and replicate. The challenges and …

ROP16-mediated activation of STAT6 enhances cyst development of type III Toxoplasma gondii in neurons

JA Kochanowsky, S Chandrasekaran… - PLoS …, 2023 - journals.plos.org
Toxoplasma gondii establishes a long-lived latent infection in the central nervous system
(CNS) of its hosts. Reactivation in immunocompromised individuals can lead to life …

The role of Nrf2 signaling in parasitic diseases and its therapeutic potential

M Vatankhah, R Panahizadeh, A Safari, A Ziyabakhsh… - Heliyon, 2024 - cell.com
In response to invading parasites, one of the principal arms of innate immunity is oxidative
stress, caused by reactive oxygen species (ROS). However, oxidative stresses play dual …

[HTML][HTML] Metabolic changes to host cells with Toxoplasma gondii infection

GM Gallego-López, EC Guzman, LJ Knoll, M Skala - bioRxiv, 2023 - ncbi.nlm.nih.gov
Toxoplasma gondii, the causative agent of toxoplasmosis, is an obligate intracellular
parasite that infects warm-blooded vertebrates across the world. In humans, seropositivity …

Seeing the unseen: illuminating Toxoplasma gondii's metabolic manipulation

D Huet, V Jeffers - Mbio, 2024 - journals.asm.org
Intracellular infection by a pathogen induces significant rewiring of host cell signaling and
biological processes. Understanding how an intracellular pathogen such as Toxoplasma …

ROP16-mediated activation of STAT6 facilitates encystment of type III Toxoplasma gondii in neurons

JA Kochanowsky, S Chandrasekaran, JR Sanchez… - bioRxiv, 2022 - biorxiv.org
Toxoplasma gondii establishes a long-lived latent infection in the central nervous system
(CNS) of its hosts. Reactivation in immunocompromised individuals can lead to life …