Biomedical polymers have been extensively developed for promising applications in a lot of
biomedical fields, such as therapeutic medicine delivery, disease detection and diagnosis …

Small-molecule prodrugs have become the main toolbox to improve the unfavorable
physicochemical properties of potential therapeutic compounds in contemporary anti-cancer …

Rational design of multifunctional nanomedicines has revolutionized the therapeutic efficacy
of cancers. Herein, we have constructed the functional nucleic acids (FNAs)-engineered …

Prodrug nanoassemblies combine the advantages of prodrug and nanomedicines, offering
great potential in targeting the lesion sites and specific on-demand drug release, maximizing …

Immunogenic cell death (ICD, also known as immunogenic apoptosis) of malignant cells is
confirmed to activate the host immune system to prevent, control, and eliminate tumors …

Cancer, with its diversity, heterogeneity, and complexity, is a significant contributor to global
morbidity, disability, and mortality, highlighting the necessity for transformative treatment …

Leukemia is a widespread hematological malignancy characterized by an elevated white
blood cell count in both the blood and the bone marrow. Despite notable advancements in …

Nanomedicines often rely on noncovalent self-assembly and encapsulation for drug loading
and delivery. However, challenges such as reproducibility issues due to the multicomponent …

Nanoparticles (NPs)‐based cancer therapeutics are generally impeded by poor drug
penetration into solid tumors due to their dense tumor extracellular matrix (ECM). Herein …

Prodrug‐based self‐assembled nanoparticles (PSNs) with tailored responses to tumor
microenvironments show a significant promise for chemodynamic therapy (CDT) by …