Circadian rhythms are internal manifestations of the solar day that permit adaptations to
predictable environmental temporal changes. These~ 24-h rhythms are controlled by …

Signs of mental ill health that cut across psychiatric diagnostic categories at high rates are
typically viewed as non-specific occurrences, downgraded in importance and disregarded …

Sleep timing is controlled by the subtle interplay between circadian and homeostatic
oscillators which, according to their endogenous properties, allow beings to feel …

Many processes in the human body—including brain function—are regulated over the 24-
hour cycle, and there are strong associations between disrupted circadian rhythms (for …

Epidemiological studies provided the first evidence suggesting a connection between the
circadian clock and human health. Mutant mice convincingly demonstrate the principle that …

In humans, sleep regulation is tightly linked to social times that assign local time to events,
such as school, work, or meals. The impact of these social times, collectively—social time …

The circadian rhythm is crucial for physiological and behavioral functions. Chronotype,
which represents individual preferences for activity and performance, is associated with …

The circadian system regulates physiology and behavior. Acute challenges to the system,
such as those experienced when traveling across time zones, will eventually result in re …

Our sleep timing preference, or chronotype, is a manifestation of our internal biological
clock. Variation in chronotype has been linked to sleep disorders, cognitive and physical …

An intimate relationship exists between sleep and affective states. Disturbances in sleep are
common across a spectrum of psychopathologies, and are recognised as precipitating or …