Cyclic di-GMP: the first 25 years of a universal bacterial second messenger

U Römling, MY Galperin… - … and Molecular Biology …, 2013 - Am Soc Microbiol
Twenty-five years have passed since the discovery of cyclic dimeric (3′→ 5′) GMP (cyclic
di-GMP or c-di-GMP). From the relative obscurity of an allosteric activator of a bacterial …

Principles of c-di-GMP signalling in bacteria

R Hengge - Nature Reviews Microbiology, 2009 - nature.com
On the stage of bacterial signal transduction and regulation, bis-(3′-5′)-cyclic dimeric
guanosine monophosphate (c-di-GMP) has long played the part of Slee** Beauty. c-di …

Biofilms and cyclic di-GMP (c-di-GMP) signaling: lessons from Pseudomonas aeruginosa and other bacteria

M Valentini, A Filloux - Journal of Biological Chemistry, 2016 - ASBMB
The cyclic di-GMP (c-di-GMP) second messenger represents a signaling system that
regulates many bacterial behaviors and is of key importance for driving the lifestyle switch …

Near-infrared fluorescent proteins, biosensors, and optogenetic tools engineered from phytochromes

KG Chernov, TA Redchuk, ES Omelina… - Chemical …, 2017 - ACS Publications
Phytochrome photoreceptors absorb far-red and near-infrared (NIR) light and regulate light
responses in plants, fungi, and bacteria. Their multidomain structure and autocatalytic …

Nucleotide, c-di-GMP, c-di-AMP, cGMP, cAMP,(p) ppGpp signaling in bacteria and implications in pathogenesis

D Kalia, G Merey, S Nakayama, Y Zheng… - Chemical Society …, 2013 - pubs.rsc.org
For an organism to survive, it must be able to sense its environment and regulate
physiological processes accordingly. Understanding how bacteria integrate signals from …

Structural and mechanistic determinants of c-di-GMP signalling

T Schirmer, U Jenal - Nature Reviews Microbiology, 2009 - nature.com
Abstract Bis-(3′-5′)-cyclic dimeric GMP (c-di-GMP) is a ubiquitous second messenger that
regulates cell surface-associated traits in bacteria. Components of this regulatory network …

Smartphone-controlled optogenetically engineered cells enable semiautomatic glucose homeostasis in diabetic mice

J Shao, S Xue, G Yu, Y Yu, X Yang, Y Bai… - Science translational …, 2017 - science.org
With the increasingly dominant role of smartphones in our lives, mobile health care systems
integrating advanced point-of-care technologies to manage chronic diseases are gaining …

Unraveling the complex regulatory networks in biofilm formation in bacteria and relevance of biofilms in environmental remediation

KU Mahto, S Kumari, S Das - Critical Reviews in Biochemistry and …, 2022 - Taylor & Francis
Biofilms are assemblages of bacteria embedded within a matrix of extracellular polymeric
substances (EPS) attached to a substratum. The process of biofilm formation is a complex …

Molecular aspects of bacterial nanocellulose biosynthesis

P Jacek, F Dourado, M Gama… - Microbial …, 2019 - Wiley Online Library
Bacterial nanocellulose (BNC) produced by aerobic bacteria is a biopolymer with
sophisticated technical properties. Although the potential for economically relevant …

Second messenger regulation of biofilm formation: breakthroughs in understanding c-di-GMP effector systems

CD Boyd, GA O'Toole - Annual review of cell and …, 2012 - annualreviews.org
The second messenger bis-(3′–5′)-cyclic dimeric guanosine monophosphate (c-di-GMP)
has emerged as a broadly conserved intracellular signaling molecule. This soluble molecule …