Focal adhesions, contractility, and signaling
K Burridge… - Annual review of cell and …, 1996 - annualreviews.org
▪ Abstract Focal adhesions are sites of tight adhesion to the underlying extracellular matrix
developed by cells in culture. They provide a structural link between the actin cytoskeleton …
developed by cells in culture. They provide a structural link between the actin cytoskeleton …
Function and genetics of dystrophin and dystrophin-related proteins in muscle
DJ Blake, A Weir, SE Newey… - Physiological …, 2002 - journals.physiology.org
The X-linked muscle-wasting disease Duchenne muscular dystrophy is caused by mutations
in the gene encoding dystrophin. There is currently no effective treatment for the disease; …
in the gene encoding dystrophin. There is currently no effective treatment for the disease; …
A role for the dystrophin-glycoprotein complex as a transmembrane linker between laminin and actin
The dystrophin-glycoprotein complex was tested for interaction with several components of
the extracellular matrix as well as actin. The 156-kD dystrophin-associated glycoprotein (156 …
the extracellular matrix as well as actin. The 156-kD dystrophin-associated glycoprotein (156 …
Primary structure of dystrophin-associated glycoproteins linking dystrophin to the extracellular matrix
O Ibraghimov-Beskrovnaya, JM Ervasti, CJ Leveille… - Nature, 1992 - nature.com
The primary sequence of two components of the dystrophin–glycoprotein complex has been
established by complementary DNA cloning. The transmembrane 43K and extracellular …
established by complementary DNA cloning. The transmembrane 43K and extracellular …
Structure and biological activity of basement membrane proteins
R Timpl - European Journal of Biochemistry, 1989 - Wiley Online Library
Collagen type IV, laminin, heparan sulfate proteoglycans, nidogen (entactin) and BM‐40
(osteonectin, SPARC) represent major structural proteins of basement membranes. They are …
(osteonectin, SPARC) represent major structural proteins of basement membranes. They are …
Dystroglycan: from biosynthesis to pathogenesis of human disease
α-and β-dystroglycan constitute a membrane-spanning complex that connects the
extracellular matrix to the cytoskeleton. Although a structural role for dystroglycan had been …
extracellular matrix to the cytoskeleton. Although a structural role for dystroglycan had been …
Structures of sialylated O-linked oligosaccharides of bovine peripheral nerve α-dystroglycan: the role of a novel O-mannosyl-type oligosaccharide in the binding of α …
α-Dystroglycan is a heavily glycosylated protein, which is localized on the Schwann cell
membrane as well as the sarcolemma, and links the transmembrane protein β-dystroglycan …
membrane as well as the sarcolemma, and links the transmembrane protein β-dystroglycan …
Dystroglycanopathies: coming into focus
A common group of muscular dystrophies is associated with the aberrant glycosylation of α-
dystroglycan. These clinically heterogeneous disorders, collectively termed …
dystroglycan. These clinically heterogeneous disorders, collectively termed …
Laminin and the mechanism of neuronal outgrowth
L Luckenbill-Edds - Brain Research Reviews, 1997 - Elsevier
This review summarizes the structure of the laminin molecule and the role it plays in
development, pathfinding and regeneration in the vertebrate nervous system. Laminin has …
development, pathfinding and regeneration in the vertebrate nervous system. Laminin has …
N-cadherin and integrins: two receptor systems that mediate neuronal process outgrowth on astrocyte surfaces
Receptor-mediated interactions between neurons and astroglia are likely to play a crucial
role in the growth and guidance of CNS axons. Using antibodies to neuronal cell surface …
role in the growth and guidance of CNS axons. Using antibodies to neuronal cell surface …