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GRP78 as a potential therapeutic target in cancer treatment: An updated review of its role in chemoradiotherapy resistance of cancer cells
M Lin, Y Mo, C Li, Y Liu, X Feng - Medical Oncology, 2025 - Springer
Abstract GRP78 (Glucose-related protein 78, BiP/HSPA5) is commonly overexpressed in
cancer cells. Acting as an activator of endoplasmic reticulum stress, GRP78 is involved in …
cancer cells. Acting as an activator of endoplasmic reticulum stress, GRP78 is involved in …
Towards the understanding of molecular motors and its relationship with local unfolding
Molecular motors are machines essential for life since they convert chemical energy into
mechanical work. However, the precise mechanism by which nucleotide binding, catalysis …
mechanical work. However, the precise mechanism by which nucleotide binding, catalysis …
QRICH1 suppresses pediatric T-cell acute lymphoblastic leukemia by inhibiting GRP78
J Zhao, M Kang, H Li, L Rong, Y Wang, Y Xue… - Cell Death & …, 2024 - nature.com
T-cell acute lymphoblastic leukemia (T-ALL) is an aggressive hematological malignancy that
commonly affects children and adolescents with a poor prognosis. The terminal unfolded …
commonly affects children and adolescents with a poor prognosis. The terminal unfolded …
Corilagin alleviated intestinal ischemia-reperfusion injury by modulating endoplasmic reticulum stress via bonding with Bip
Y Wang, G Liu, F Qiu, X Li, Y Diao, M Yang, S Yang… - Phytomedicine, 2024 - Elsevier
Background Intestinal ischemia-reperfusion (II/R) injury is a common clinical emergency with
high morbidity and mortality. Given the absence of efficacious prophylactic and therapeutic …
high morbidity and mortality. Given the absence of efficacious prophylactic and therapeutic …
Optical scattering methods for the label-free analysis of single biomolecules
Single-molecule techniques to analyze proteins and other biomolecules involving labels
and tethers have allowed for new understanding of the underlying biophysics; however, the …
and tethers have allowed for new understanding of the underlying biophysics; however, the …