Endocrine regulation of epimorphic regeneration

MR Easterling, KM Engbrecht, EJ Crespi - Endocrinology, 2019‏ - academic.oup.com
Studies aiming to uncover primary mechanisms of regeneration have predominantly focused
on genetic pathways regulating specific stages in the regeneration process: wound healing …

Leptin promotes wound healing in the skin

S Tadokoro, S Ide, R Tokuyama, H Umeki, S Tatehara… - PloS one, 2015‏ - journals.plos.org
Introduction Leptin, a 16 kDa anti-obesity hormone, exhibits various physiological
properties. Interestingly, skin wound healing was proven to delay in leptin-deficient ob/ob …

[HTML][HTML] Insulin, not leptin, promotes in vitro cell migration to heal monolayer wounds in human corneal epithelium

LJ Shanley, CD McCaig, JV Forrester… - … ophthalmology & visual …, 2004‏ - arvojournals.org
purpose. To investigate the effects of insulin and leptin on in vitro wound healing of
transformed human corneal epithelial cell monolayers and to identify cellular (migration …

Leptin reverses the inhibitory effect of caloric restriction on longitudinal growth

G Gat-Yablonski, T Ben-Ari, B Shtaif, O Potievsky… - …, 2004‏ - academic.oup.com
Caloric imbalance, particularly in critical periods of growth and development, is often the
underlying cause of growth abnormalities. Serum levels of leptin are elevated in obesity and …

Endocrine regulation of regeneration: Linking global signals to local processes

MR Easterling, KM Engbrecht, EJ Crespi - General and Comparative …, 2019‏ - Elsevier
Regeneration in amphibians and reptiles has been explored since the early 18th century,
giving us a working in vivo model to study epimorphic regeneration in vertebrates. Studies …

[HTML][HTML] Nuclear Factor-Y is an adipogenic factor that regulates leptin gene expression

YH Lu, OS Dallner, K Birsoy, G Fayzikhodjaeva… - Molecular …, 2015‏ - Elsevier
Objective Leptin gene expression is highly correlated with cellular lipid content in adipocytes
but the transcriptional mechanisms controlling leptin expression in vivo are poorly …

Leptin inhibits cell growth of human vascular smooth muscle cells

F Bohlen, J Kratzsch, M Mueller, B Seidel… - Vascular …, 2007‏ - Elsevier
Elevated leptin levels are thought to contribute to the individual cardiovascular risk,
however, the role of leptin in the pathogenesis of atherosclerosis remains unclear. The aim …

[PDF][PDF] Monitoring leptin activity using the chicken leptin receptor

G Hen, S Yosefi, A Ronin, P Einat… - Journal of …, 2008‏ - academia.edu
We report on the construction of a leptin bioassay based on the activation of chicken leptin
receptor in cultured cells. A human embryonic kidney (HEK)-293 cell line, stably transfected …

GH prevents apoptosis in cardiomyocytes cultured in vitro through a calcineurin-dependent mechanism

R Pineiro, MJ Iglesias, O Gualillo… - Journal of …, 2004‏ - joe.bioscientifica.com
The effect of carbachol (Cch) on intracellular calcium concentration ([Ca2+] i) in eel
enterocytes was examined using the fluorescent Ca2+ indicator fura-2. Cch caused a …

[PDF][PDF] Lack of leptin activity in blood samples of Adélie penguin and bar-tailed godwit

S Yosefi, G Hen, CI Rosenblum, DJ Cerasale… - Journal of …, 2010‏ - academia.edu
Unsuccessful attempts to identify the leptin gene in birds are well documented, despite the
characterization of its receptor (LEPR). Since leptin and LEPR have poor sequence …