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Axial spondyloarthritis
Axial spondyloarthritis (axSpA) encompasses both radiographic and non-radiographic
axSpA. It is a chronic inflammatory disease with a predilection for involving the axial …
axSpA. It is a chronic inflammatory disease with a predilection for involving the axial …
2016 update of the ASAS-EULAR management recommendations for axial spondyloarthritis
D Van Der Heijde, S Ramiro, R Landewé… - Annals of the rheumatic …, 2017 - Elsevier
To update and integrate the recommendations for ankylosing spondylitis and the
recommendations for the use of tumour necrosis factor inhibitors (TNFi) in axial …
recommendations for the use of tumour necrosis factor inhibitors (TNFi) in axial …
EULAR recommendations for the use of imaging in the diagnosis and management of spondyloarthritis in clinical practice
A taskforce comprised of an expert group of 21 rheumatologists, radiologists and
methodologists from 11 countries developed evidence-based recommendations on the use …
methodologists from 11 countries developed evidence-based recommendations on the use …
Spondyloarthritis
M Dougados, D Baeten - The Lancet, 2011 - thelancet.com
Spondyloarthritis is a group of several related but phenotypically distinct disorders: psoriatic
arthritis, arthritis related to inflammatory bowel disease, reactive arthritis, a subgroup of …
arthritis, arthritis related to inflammatory bowel disease, reactive arthritis, a subgroup of …
Proof of concept: enthesitis and new bone formation in spondyloarthritis are driven by mechanical strain and stromal cells
P Jacques, S Lambrecht, E Verheugen… - Annals of the …, 2014 - ard.bmj.com
Objectives Spondyloarthritides (SpA) are characterised by both peripheral and axial arthritis.
The hallmarks of peripheral SpA are the development of enthesitis, most typically of the …
The hallmarks of peripheral SpA are the development of enthesitis, most typically of the …
Effect of continuous versus on-demand treatment of ankylosing spondylitis with diclofenac over 2 years on radiographic progression of the spine: results from a …
Background To date, only a single controlled trial provided evidence that non-steroidal anti-
inflammatory drugs (NSAIDs) given continuously reduce radiographic progression …
inflammatory drugs (NSAIDs) given continuously reduce radiographic progression …
Continuous long-term anti-TNF therapy does not lead to an increase in the rate of new bone formation over 8 years in patients with ankylosing spondylitis
Objective Compare the radiographic progression of ankylosing spondylitis (AS) patients
treated with infliximab (INF) versus historical controls (Herne cohort, HC) never treated with …
treated with infliximab (INF) versus historical controls (Herne cohort, HC) never treated with …
Patient burden of axial spondyloarthritis
Axial spondyloarthritis (AxSpA) is an inflammatory spondyloarthritis (SpA) that has
significant impact on a patient's life. Symptoms, including fatigue, sleep problems …
significant impact on a patient's life. Symptoms, including fatigue, sleep problems …
Assessment of radiographic progression in the spines of patients with ankylosing spondylitis treated with adalimumab for up to 2 years
D van der Heijde, D Salonen, BN Weissman… - Arthritis research & …, 2009 - Springer
Introduction Ankylosing spondylitis (AS) is a chronic rheumatic disease associated with
spinal inflammation that subsequently leads to progression of structural damage and loss of …
spinal inflammation that subsequently leads to progression of structural damage and loss of …
Altered skeletal expression of sclerostin and its link to radiographic progression in ankylosing spondylitis
H Appel, G Ruiz‐Heiland, J Listing… - … : Official Journal of …, 2009 - Wiley Online Library
Objective Osteocytes are considered to be sensors of bone damage and regulators of bone
mass by specifically expressing sclerostin, an inhibitor of bone formation. The contribution of …
mass by specifically expressing sclerostin, an inhibitor of bone formation. The contribution of …