Biopharmaceutical applications of microbial polysaccharides as materials: a review

Y Song, S Li, H Gong, RCS Yip, H Chen - International Journal of Biological …, 2023‏ - Elsevier
Biological characteristics of natural polymers make microbial polysaccharides an excellent
choice for biopharmaceuticals. Due to its easy purifying procedure and high production …

Seaweed sulfated polysaccharides and their medicinal properties

OO Zaitseva, MI Sergushkina, AN Khudyakov… - Algal Research, 2022‏ - Elsevier
Currently, biologically active natural products become more and more popular among
consumers, both in the form of food supplements and cosmetic products, and as medicines …

[HTML][HTML] Cartilage-inspired self-assembly glycopeptide hydrogels for cartilage regeneration via ROS scavenging

Z Zhao, X **a, J Liu, M Hou, Y Liu, Z Zhou, Y Xu, F He… - Bioactive Materials, 2024‏ - Elsevier
Cartilage injury represents a frequent dilemma in clinical practice owing to its inherently
limited self-renewal capacity. Biomimetic strategy-based engineered biomaterial, capable of …

Fucoidan Improves Early Stage Diabetic Nephropathy via the Gut Microbiota–Mitochondria Axis in High-Fat Diet-Induced Diabetic Mice

Z Zhong, Y Zhang, Y Wei, X Li, L Ren, Y Li… - Journal of Agricultural …, 2024‏ - ACS Publications
Diabetic nephropathy (DN) is a common microvascular complication of diabetes. Fucoidan,
a polysaccharide containing fucose and sulfate group, ameliorates DN. However, the …

Nano-sized fucoidan interpolyelectrolyte complexes: recent advances in design and prospects for biomedical applications

NV Dubashynskaya, ER Gasilova… - International Journal of …, 2023‏ - mdpi.com
The marine polysaccharide fucoidan (FUC) is a promising polymer for pharmaceutical
research and development of novel drug delivery systems with modified release and …

Therapeutic effect of natural products and dietary supplements on aflatoxin-induced nephropathy

E Ofori-Attah, M Hashimoto, M Oki… - International Journal of …, 2024‏ - mdpi.com
Aflatoxins are harmful natural contaminants found in foods and are known to be hepatotoxic.
However, recent studies have linked chronic consumption of aflatoxins to nephrotoxicity in …

Fucoidan-based nanomaterial and its multifunctional role for pharmaceutical and biomedical applications

MW Iqbal, T Riaz, S Mahmood, M Bilal… - Critical Reviews in …, 2024‏ - Taylor & Francis
Fucoidans are promising sulfated polysaccharides isolated from marine sources that have
piqued the interest of scientists in recent years due to their widespread use as a bioactive …

Fucoidan modulates gut microbiota and immunity in Peyer's patches against inflammatory bowel disease

JK Li, S Veeraperumal, JJ Aweya, Y Liu… - Carbohydrate …, 2024‏ - Elsevier
Although fucoidan has potential use as an anti-inflammatory agent, the specific mechanisms
by which it influences signaling and immunomodulatory pathways between gut microbiota …

[HTML][HTML] Fucoidans: Exploring its neuroprotective mechanisms and therapeutic applications in brain disorders

P Batista, SA Cunha, T Ribeiro, S Borges… - Trends in food science & …, 2024‏ - Elsevier
Background Marine-derived natural products have been attracting attention from both the
food and pharmaceutical sectors due to their promising therapeutic attributes. Algae and …

[HTML][HTML] Fucoidan protects against doxorubicin-induced cardiotoxicity by reducing oxidative stress and preventing mitochondrial function injury

Y Ji, D **, J Qi, X Wang, C Zhang, P An, Y Luo… - International Journal of …, 2022‏ - mdpi.com
Doxorubicin (DOXO) is a potent chemotherapeutic drug widely used to treat various cancers.
However, its clinical application is limited due to serious adverse effects on dose-dependent …