Microbiota medicine: towards clinical revolution

P Gebrayel, C Nicco, S Al Khodor, J Bilinski… - Journal of translational …, 2022 - Springer
The human gastrointestinal tract is inhabited by the largest microbial community within the
human body consisting of trillions of microbes called gut microbiota. The normal flora is the …

[HTML][HTML] Drug-microbiota interactions: an emerging priority for precision medicine

Q Zhao, Y Chen, W Huang, H Zhou… - Signal Transduction and …, 2023 - nature.com
Individual variability in drug response (IVDR) can be a major cause of adverse drug
reactions (ADRs) and prolonged therapy, resulting in a substantial health and economic …

[HTML][HTML] Prebiotic potential of apple pomace and pectins from different apple varieties: Modulatory effects on key target commensal microbial populations

I Calvete-Torre, C Sabater, MJ Antón, FJ Moreno… - Food …, 2022 - Elsevier
Pectin is a group of structurally diverse dietary fibers, very abundant in agri-food waste and
by-products such as those generated during apple cider manufacturing. In recent years …

Recent updates on correlation between reactive oxygen species and synbiotics for effective management of ulcerative colitis

S Ashique, N Mishra, A Garg, BZ Sibuh, P Taneja… - Frontiers in …, 2023 - frontiersin.org
Ulcerative colitis (UC) is presently considered a multifactorial pathology, which may lead to
persistent inflammatory action of the gastrointestinal tract (GIT) because of an improperly …

[HTML][HTML] Homeostasis and dysbiosis of the intestinal microbiota: comparing hallmarks of a healthy state with changes in inflammatory bowel disease

J Talapko, A Včev, T Meštrović, E Pustijanac, M Jukić… - Microorganisms, 2022 - mdpi.com
The gut microbiota, which represent a community of different microorganisms in the human
intestinal tract, are crucial to preserving human health by participating in various …

Microbiome dynamics: a paradigm shift in combatting infectious diseases

M Kamel, S Aleya, M Alsubih, L Aleya - Journal of Personalized Medicine, 2024 - mdpi.com
Infectious diseases have long posed a significant threat to global health and require
constant innovation in treatment approaches. However, recent groundbreaking research has …

Diversity of the microbiota communities found in the various regions of the intestinal tract in healthy individuals and inflammatory bowel diseases

SA Lawal, A Voisin, H Olof… - Frontiers in …, 2023 - frontiersin.org
The severe and chronic inflammatory bowel diseases (IBD), Crohn disease and ulcerative
colitis, are characterized by persistent inflammation and gut damage. There is an increasing …

[HTML][HTML] Antibacterial compounds-incorporated functional biomaterials for chronic wound healing application via 3D bioprinting: The mechanism of action

NIM Fadilah, NAAK Nizam, MB Fauzi - International Journal of …, 2024 - accscience.com
Wounds represent a critical issue in the healthcare industry since they are highly susceptible
to infections that in turn lead to more serious complications. With bacterial infections …

Composition of the gut microbiota in patients with inflammatory bowel disease in Saudi Arabia: A pilot study

H Al-Amrah, OI Saadah, M Mosli… - Saudi Journal of …, 2023 - journals.lww.com
Background: Inflammatory bowel disease (IBD) is a chronic intestinal inflammatory condition
attributed to a complex interaction between imbalances in the gut microbiome …

Fecal microbiota transplantation and next-generation therapies: A review on targeting dysbiosis in metabolic disorders and beyond

Z Sahle, G Engidaye… - SAGE Open …, 2024 - journals.sagepub.com
The human microbiome, particularly the gut microbiome, has emerged as a central
determinant of health and disease. Dysbiosis, an imbalance in the microbial composition of …