Considerable progress has been made in develo** models of cerebellar function in
sensorimotor control, as well as in identifying key problems that are the focus of current …

Work over the past 2 decades has led to substantial changes in our understanding of
dystonia pathophysiology. Three general abnormalities appear to underlie the …

Objectives: To provide a revised version of earlier guidelines published in 2006.
Background: Primary dystonias are chronic and often disabling conditions with a …

Dystonia is a neurological disorder characterized by involuntary twisting movements and
postures. There are many different clinical manifestations, and many different causes. The …

Background The dystonias include a clinically and etiologically very diverse group of
disorders. There are both degenerative and non-degenerative subtypes resulting from …

A role for the cerebellum in causing ataxia, a disorder characterized by uncoordinated
movement, is widely accepted. Recent work has suggested that alterations in activity …

The dystonias are a group of disorders defined by sustained or intermittent muscle
contractions that result in involuntary posturing or repetitive movements. There are many …

Time perception is an essential element of conscious and subconscious experience,
coordinating our perception and interaction with the surrounding environment. In recent …

In recent years, gene therapy based on miRNA has been employed as a potential growing
technique for treating various co-morbidities. Direct administration of miRNA is unrealistic …

The cerebellum has a well-established role in maintaining motor coordination and studies of
cerebellar learning suggest that it does this by recognizing neural patterns, which it uses to …