Form follows function: nanoparticle shape and its implications for nanomedicine
This review is a comprehensive description of the past decade of research into
understanding how the geometry and size of nanoparticles affect their interaction with …
understanding how the geometry and size of nanoparticles affect their interaction with …
Converting nanotoxicity data to information using artificial intelligence and simulation
Decades of nanotoxicology research have generated extensive and diverse data sets.
However, data is not equal to information. The question is how to extract critical information …
However, data is not equal to information. The question is how to extract critical information …
Shape and orientation matter for the cellular uptake of nonspherical particles
Recent advances in nanotechnology have made a whole zoo of particles of different shapes
available for applications, but their interaction with biological cells and their toxicity is often …
available for applications, but their interaction with biological cells and their toxicity is often …
Curving cells inside and out: roles of BAR domain proteins in membrane sha** and its cellular implications
M Simunovic, E Evergren… - Annual review of cell …, 2019 - annualreviews.org
Many cellular processes rely on precise and timely deformation of the cell membrane. While
many proteins participate in membrane resha** and scission, usually in highly specialized …
many proteins participate in membrane resha** and scission, usually in highly specialized …
Theoretical and computational investigations of nanoparticle–biomembrane interactions in cellular delivery
H Ding, Y Ma - Small, 2015 - Wiley Online Library
With the rapid development of nanotechnology, nanoparticles have been widely used in
many applications such as phototherapy, cell imaging, and drug/gene delivery. A better …
many applications such as phototherapy, cell imaging, and drug/gene delivery. A better …
Mechanical force induces mitochondrial fission
Eukaryotic cells are densely packed with macromolecular complexes and intertwining
organelles, continually transported and reshaped. Intriguingly, organelles avoid clashing …
organelles, continually transported and reshaped. Intriguingly, organelles avoid clashing …
Wrap** of nanoparticles by membranes
How nanoparticles interact with biomembranes is central for understanding their bioactivity.
Biomembranes wrap around nanoparticles if the adhesive interaction between the …
Biomembranes wrap around nanoparticles if the adhesive interaction between the …
Critical particle sizes for the engulfment of nanoparticles by membranes and vesicles with bilayer asymmetry
The adhesion and engulfment of nanoparticles by biomembranes is essential for many
processes such as biomedical imaging, drug delivery, nanotoxicity, and viral infection. Many …
processes such as biomedical imaging, drug delivery, nanotoxicity, and viral infection. Many …
Membrane tension controls the assembly of curvature-generating proteins
Abstract Proteins containing a Bin/Amphiphysin/Rvs (BAR) domain regulate membrane
curvature in the cell. Recent simulations have revealed that BAR proteins assemble into …
curvature in the cell. Recent simulations have revealed that BAR proteins assemble into …
Linear aggregation of proteins on the membrane as a prelude to membrane remodeling
Adhesion and insertion of curvature-mediating proteins can induce dramatic structural
changes in cell membranes, allowing them to participate in several key cellular tasks. The …
changes in cell membranes, allowing them to participate in several key cellular tasks. The …