Cationic host defence peptides (CHDP), also known as antimicrobial peptides, are naturally
occurring peptides that can combat infections through their direct microbicidal properties …

Defensins are a major family of host defense peptides expressed predominantly in
neutrophils and epithelial cells. Their broad antimicrobial activities and multifaceted …

This review looks at the critical role of vitamin D in improving barrier function, production of
antimicrobial peptides including cathelicidin and some defensins, and immune modulation …

Defensins are an effector component of the innate immune system with broad antimicrobial
activity. Humans express two types of defensins, α-and β-defensins, which have antiviral …

The last decade led to the discovery and characterization of several human β-defensins.
Analysis of genomic information indicates that the number of β-defensin-like molecules …

Defensins are small antimicrobial peptides that are produced by leukocytes and epithelial
cells, and that have an important role in innate immunity. Recent advances in understanding …

A group of interesting molecules called defensins exhibit multiple functions but have been
primarily recognized to possess a broad spectrum of antimicrobial activities. Studies have …

α, β, and θ defensins are effectors of the innate immune system with potent antibacterial,
antiviral, and antifungal activity. Defensins have direct antiviral activity in cell culture, with …

Infectious diseases caused by bacteria, viruses or fungi are among the leading causes of
death worldwide. The emergence of drug-resistance mechanisms, especially among …

A safe, potent and broad-spectrum antiviral is urgently needed to combat emerging
respiratory viruses. In light of the broad antiviral activity of β-defensins, we tested the antiviral …