Human antimicrobial peptides as therapeutics for viral infections
A Ahmed, G Siman-Tov, G Hall, N Bhalla, A Narayanan - Viruses, 2019 - mdpi.com
Successful in vivo infection following pathogen entry requires the evasion and subversion of
multiple immunological barriers. Antimicrobial peptides (AMPs) are one of the first immune …
multiple immunological barriers. Antimicrobial peptides (AMPs) are one of the first immune …
Immunomodulatory role of the antimicrobial LL-37 peptide in autoimmune diseases and viral infections
Antimicrobial peptides (AMPs) are produced by neutrophils, monocytes, and macrophages,
as well as epithelial cells, and are an essential component of innate immunity system …
as well as epithelial cells, and are an essential component of innate immunity system …
Immunological aspects of SARS-CoV-2 infection and the putative beneficial role of vitamin-D
MY Peng, WC Liu, JQ Zheng, CL Lu, YC Hou… - International journal of …, 2021 - mdpi.com
Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome
coronavirus-2 (SARS-CoV-2) is still an ongoing global health crisis. Immediately after the …
coronavirus-2 (SARS-CoV-2) is still an ongoing global health crisis. Immediately after the …
Human β-defensin 2 plays a regulatory role in innate antiviral immunity and is capable of potentiating the induction of antigen-specific immunity
J Kim, YL Yang, SH Jang, YS Jang - Virology journal, 2018 - Springer
Abstract Background Antimicrobial peptides (AMPs) are primarily known for their innate
immune defense against invading microorganisms, including viruses. In addition, recent …
immune defense against invading microorganisms, including viruses. In addition, recent …
Antiviral activities of human host defense peptides
Peptides with broad-spectrum antimicrobial activity are found widely expressed throughout
nature. As they participate in a number of different aspects of innate immunity in mammals …
nature. As they participate in a number of different aspects of innate immunity in mammals …
[HTML][HTML] Towards the application of human defensins as antivirals
Defensins are antimicrobial peptides that participate in the innate immunity of hosts.
Humans constitutively and/or inducibly express α-and β-defensins, which are known for their …
Humans constitutively and/or inducibly express α-and β-defensins, which are known for their …
In-vitro effect of human cathelicidin antimicrobial peptide LL-37 on dengue virus type 2
Human Cathelicidin antimicrobial peptide LL-37 is known to have antiviral activity against
many viruses. In the present study, we investigated the in-vitro effect of LL-37 on dengue …
many viruses. In the present study, we investigated the in-vitro effect of LL-37 on dengue …
Vitamin D-induced LL-37 modulates innate immune responses of human primary macrophages during DENV-2 infection
Epidemics of dengue, an acute and potentially severe disease caused by mosquito-borne
dengue virus (DENV), pose a major challenge to clinicians and health care services across …
dengue virus (DENV), pose a major challenge to clinicians and health care services across …
Endogenous cathelicidin is required for protection against ZIKV-caused testis damage via inactivating virons
Z Liu, J Wu, Z Qin, C Dong, H Yang, J Sun, W Xu… - Antiviral Research, 2022 - Elsevier
Cathelicidins have been shown to effectively inhibit flavivirus replication in vitro. However,
the effects of mouse and human endogenous cathelicidins on flavivirus infection in vivo are …
the effects of mouse and human endogenous cathelicidins on flavivirus infection in vivo are …
Cathelicidins target hsp60 to restrict cvb3 transmission via disrupting the exosome and reducing cardiomyocyte apoptosis
Y Yang, C Huang, L Hui, Y Song, Y Fu, M Li… - Journal of …, 2023 - Am Soc Microbiol
Cathelicidin antimicrobial peptides (mouse, CRAMP; human, LL-37) have broad-spectrum
antiviral activities against enveloped viruses, but their mechanisms of action against …
antiviral activities against enveloped viruses, but their mechanisms of action against …