Infertility is a global health problem involving about 15% of couples. Approximately half of
the infertility cases are related to male factors. The oxidative stress, which refers to an …

Gene transcription can be activated or inhibited by a reversible modification of the gene; this
modification is termed an epigenetic change. This account of epigenetics in cancer reviews …

As studies of DNA methylation increase in scope, it has become evident that methylation has
a complex relationship with gene expression, plays an important role in defining cell types …

DNA methylation is a crucial epigenetic modification of the genome that is involved in
regulating many cellular processes. These include embryonic development, transcription …

Epigenetic mechanisms play a crucial role in regulating gene expression. The main
mechanisms involve methylation of DNA and covalent modifications of histones by …

▪ Abstract Aberrant DNA methylation is the most common molecular lesion of the cancer cell.
Neither gene mutations (nucleotide changes, deletions, recombinations) nor cytogenetic …

The biochemistry of aging is complex, with biologically significant changes occurring in
proteins, lipids and nucleic acids. One of these changes is in the methylation of DNA. DNA …

Bypassing cellular senescence and becoming immortal is a prerequisite step in the
tumorigenic transformation of a cell. It has long been known that loss of a key tumor …

The accurate prediction of male fertility is of major economic importance in the animal
breeding industry. However, the results of conventional semen analysis do not always …

Clinical signs and symptoms, as well as medical and dental history, are all considered in the
clinical determination of gingival inflammation and periodontal disease severity. However …