Interstitial lung diseases
Over 200 interstitial lung diseases, from ultra rare to relatively common, are recognised.
Most interstitial lung diseases are characterised by inflammation or fibrosis within the …
Most interstitial lung diseases are characterised by inflammation or fibrosis within the …
Idiopathic pulmonary fibrosis: Disease mechanisms and drug development
P Spagnolo, JA Kropski, MG Jones, JS Lee… - Pharmacology & …, 2021 - Elsevier
Idiopathic pulmonary fibrosis (IPF) is a chronic progressive disease of unknown cause
characterized by relentless scarring of the lung parenchyma leading to reduced quality of life …
characterized by relentless scarring of the lung parenchyma leading to reduced quality of life …
[HTML][HTML] Consensus document for the selection of lung transplant candidates: an update from the International Society for Heart and Lung Transplantation
Tens of thousands of patients with advanced lung diseases may be eligible to be considered
as potential candidates for lung transplant around the world each year. The timing of referral …
as potential candidates for lung transplant around the world each year. The timing of referral …
Progressive fibrosing interstitial lung disease: clinical uncertainties, consensus recommendations, and research priorities
Within the spectrum of fibrosing interstitial lung diseases (ILDs) is a subset of patients who
have inexorable progression of pulmonary fibrosis despite treatment, which is known as the …
have inexorable progression of pulmonary fibrosis despite treatment, which is known as the …
Mechanisms of progressive fibrosis in connective tissue disease (CTD)-associated interstitial lung diseases (ILDs)
P Spagnolo, O Distler, CJ Ryerson… - Annals of the …, 2021 - ard.bmj.com
Interstitial lung diseases (ILDs), which can arise from a broad spectrum of distinct
aetiologies, can manifest as a pulmonary complication of an underlying autoimmune and …
aetiologies, can manifest as a pulmonary complication of an underlying autoimmune and …
The natural history of progressive fibrosing interstitial lung diseases
M Kolb, M Vašáková - Respiratory research, 2019 - Springer
A proportion of patients with certain types of interstitial lung disease (ILD), including chronic
hypersensitivity pneumonitis and ILDs associated with autoimmune diseases, develop a …
hypersensitivity pneumonitis and ILDs associated with autoimmune diseases, develop a …
Treatment of fibrotic interstitial lung disease: current approaches and future directions
Fibrotic interstitial lung disease (ILD) represents a large group of pulmonary disorders that
are often progressive and associated with high morbidity and early mortality. Important …
are often progressive and associated with high morbidity and early mortality. Important …
Interstitial lung disease in connective tissue disease: a common lesion with heterogeneous mechanisms and treatment considerations
T Shao, X Shi, S Yang, W Zhang, X Li, J Shu… - Frontiers in …, 2021 - frontiersin.org
Connective tissue disease (CTD) related interstitial lung disease (CTD-ILD) is one of the
leading causes of morbidity and mortality of CTD. Clinically, CTD-ILD is highly heterogenous …
leading causes of morbidity and mortality of CTD. Clinically, CTD-ILD is highly heterogenous …
Immune mechanisms in fibrotic interstitial lung disease
M Kamiya, H Carter, MS Espindola, TJ Doyle, JS Lee… - Cell, 2024 - cell.com
Fibrotic interstitial lung diseases (fILDs) have poor survival rates and lack effective therapies.
Despite evidence for immune mechanisms in lung fibrosis, immunotherapies have been …
Despite evidence for immune mechanisms in lung fibrosis, immunotherapies have been …
Telomere length associates with chronological age and mortality across racially diverse pulmonary fibrosis cohorts
A Adegunsoye, CA Newton, JM Oldham, B Ley… - Nature …, 2023 - nature.com
Pulmonary fibrosis (PF) is characterized by profound scarring and poor survival. We
investigated the association of leukocyte telomere length (LTL) with chronological age and …
investigated the association of leukocyte telomere length (LTL) with chronological age and …