Abstract Purpose of Review Adrenocortical carcinoma (ACC) is a rare endocrine malignancy
typically with poor prognosis. This review aims to summarize the current knowledge …

Mucosal melanoma is a rare subtype of melanoma. To date, there has been no
comprehensive systematic collation and statistical analysis of the aberrations and …

CTNNB1, encoding β-catenin protein, is the most frequently altered proto-oncogene in
hepatic neoplasms. In this study, we studied the significance and pathological mechanism of …

Adrenocortical carcinoma (ACC) is an uncommon, aggressive endocrine malignancy with a
high rate of recurrence, a poor prognosis, and a propensity for metastasis. Currently, only …

The human adrenal cortex is a complex endocrine organ that produces mineralocorticoids,
glucocorticoids and androgens. These steroids are produced in distinct cell types located …

Adrenocortical Carcinoma (ACC) is a rare but aggressive malignancy with poor prognosis
and limited response to available systemic therapies. Although complete surgical resection …

Objective Adrenal cortical carcinoma (ACC) is a rare malignancy with a generally poor but
heterogeneous prognosis, especially depending on the tumour stage at diagnosis …

PURPOSE Pediatric adrenocortical carcinomas (ACCs) are aggressive; the overall survival
of patients with ACCs is 40%-50%. Appropriate staging and histologic classification are …

Integrin, beta-like 1 (ITGBL1) protein is located in the extracellular matrix (ECM) and
involved in the development and metastasis of many tumors. However, the regulatory …

Abstract Background At presentation, 21% to 49% of patients with adrenocortical cancer
have metastases. Standard chemotherapy has a 23% response rate. We assessed whether …