Metal–organic frameworks for biomedical applications

J Yang, YW Yang - Small, 2020 - Wiley Online Library
Metal–organic frameworks (MOFs) are an interesting and useful class of coordination
polymers, constructed from metal ion/cluster nodes and functional organic ligands through …

Catalase‐like nanozymes: Classification, catalytic mechanisms, and their applications

D Xu, L Wu, H Yao, L Zhao - Small, 2022 - Wiley Online Library
The field of nanozymes has developed rapidly over the past decade. Among various
oxidoreductases mimics, catalase (CAT)‐like nanozyme, acting as an essential part of the …

GSH‐depleted nanozymes with hyperthermia‐enhanced dual enzyme‐mimic activities for tumor nanocatalytic therapy

S Dong, Y Dong, T Jia, S Liu, J Liu, D Yang… - Advanced …, 2020 - Wiley Online Library
Nanocatalytic therapy, using artificial nanoscale enzyme mimics (nanozymes), is an
emerging technology for therapeutic treatment of various malignant tumors. However, the …

Supramolecular cancer nanotheranostics

J Zhou, L Rao, G Yu, TR Cook, X Chen… - Chemical Society …, 2021 - pubs.rsc.org
Among the many challenges in medicine, the treatment and cure of cancer remains an
outstanding goal given the complexity and diversity of the disease. Nanotheranostics, the …

Nanoscale MOFs: From synthesis to drug delivery and theranostics applications

M Ding, W Liu, R Gref - Advanced Drug Delivery Reviews, 2022 - Elsevier
Since the first report in 1989, Metal-Organic Frameworks (MOFs) self-assembled from metal
ions or clusters, as well as organic linkers, have attracted extensive attention. Due to their …

[HTML][HTML] Multifunctional metal-organic framework (MOF)-based nanoplatforms for cancer therapy: from single to combination therapy

J Yang, D Dai, X Zhang, L Teng, L Ma, YW Yang - Theranostics, 2023 - ncbi.nlm.nih.gov
Cancer remains a severe threat to human health. To date, although various therapeutic
methods, including radiotherapy (RT), chemotherapy, chemodynamic therapy (CDT) …

Recent progress of supramolecular chemotherapy based on host–guest interactions

M Yan, S Wu, Y Wang, M Liang, M Wang… - Advanced …, 2024 - Wiley Online Library
Chemotherapy is widely recognized as an effective approach for treating cancer due to its
ability to eliminate cancer cells using chemotherapeutic drugs. However, traditional …

Biomineralized MnO2 Nanoplatforms Mediated Delivery of Immune Checkpoint Inhibitors with STING Pathway Activation to Potentiate Cancer Radio-Immunotherapy

Z Deng, M **, C Zhang, X Wu, Q Li, C Wang, H Fang… - ACS …, 2023 - ACS Publications
Radiotherapy (RT), as one of the main methods in the clinical treatment of various malignant
tumors, would induce systemic immunotherapeutic effects by triggering immunogenic cell …

Boosting checkpoint immunotherapy with biomaterials

L Liu, Y Pan, C Zhao, P Huang, X Chen, L Rao - ACS nano, 2023 - ACS Publications
The immune checkpoint blockade (ICB) therapy has revolutionized the field of cancer
treatment, while low response rates and systemic toxicity limit its clinical outcomes. With the …

Biomedical metal–organic framework materials: perspectives and challenges

A Wang, M Walden, R Ettlinger… - Advanced functional …, 2024 - Wiley Online Library
Metal–organic framework (MOF) materials are gaining significant interest in biomedical
research, owing to their high porosity, crystallinity, and structural and compositional diversity …